Cold Spring Harbor Laboratory (CSHL) researchers have identified a function of neuregulin1 (NRG1), a gene previously linked to schizophrenia but whose role in the disease was unknown. "We found that when this gene or this pathway is impaired," explained CSHL's Bo Li. "It starts a chain reaction negatively impacting synapses in the brain which contribute to the abnormal development of brain circuits and may lead to schizophrenia."

By discovering the connections between genes and how they impact synapses and circuits in the brain, research is guiding the development of new strategies to diagnose and treat neurological disease.

The discovery of a flexible genetic coding in leaf-cutting ants sheds new light on how one of nature's ultimate self-organising species breeds optimum numbers of each worker type to ensure the smooth running of the colony.

Research at the University of Leeds shows that despite an inherited genetic pre-disposition to grow into a particular worker caste, ant larvae can be triggered by environmental stimuli to switch development depending on colony's workforce needs.

Effector proteins are the bad guys that help bacterial pathogens do their job of infecting the host by crippling the body's immune system. In essence, they knock down the front door of resistance and disarm the cell's alarm system.

Now, researchers at the University of California, San Diego (UCSD) School of Medicine have identified a novel molecular target for an effector protein called YpkA, one of several effectors of the bacteria Yersinia – the pathogen responsible for the Middle Ages' "Black Death" and a virulent form of food poisoning today. Their study will be published online in the May 25 issue of Molecular Cell.

The frequency of intense hurricanes in the Atlantic Ocean appears to be closely connected to long-term trends in the El Niño/Southern Oscillation (ENSO) and the West African monsoon, according to new research from the Woods Hole Oceanographic Institution (WHOI). Geologists Jeff Donnelly and Jonathan Woodruff made that discovery while assembling the longest-ever record of hurricane strikes in the Atlantic basin.

A popular stereotype that boys are better at mathematics than girls undermines girls' math performance because it causes worrying that erodes the mental resources needed for problem solving, new research at the University of Chicago shows.

The scholars found that the worrying undermines women's working memory. Working memory is a short-term memory system involved in the control, regulation and active maintenance of limited information needed immediately to deal with problems at hand.

Integrating bio-chemical sensors into textiles for continuous monitoring of a person's health is the goal of the EU-funded BIOTEX ('Bio-sensing textile for health management') project.

As the first of its kind, the project is developing optimal electric, electrochemical and optical sensors which will be embedded into a textile substrate to create 'sensing patches' able to monitor the biochemical parameters of a user.