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Thanks to Buck and Axel and colleagues, most neuroscientists are aware of the precise topographical map of the mouse olfactory nerve projection in which each olfactory sensory neuron (OSN) expresses a single odorant receptor (OR), and OSNs expressing a given OR converge on a set of glomeruli in the olfactory bulb. This week, Sato et al. mapped the zebrafish axonal projection using a bacterial artificial chromosome transgene. The transgene contained a cluster of 16 OR genes, two of which (OR111–7 and OR103–1) were replaced with yellow and cyan membrane-targeted reporters. Distinct sets of OSNs were fluorescently labeled, whereas their axons targeted the same cluster of glomeruli.

How can defense or intelligence agencies safeguard the security of top-secret data protected by a computation device the size of a single molecule?

With cryptography approaching that sobering new era, scientists in Israel are reporting development of what they term the first molecular system capable of processing password entries. Abraham Shanzer and colleagues describe their "molecular keypad lock" in the Jan. 17 issue of the weekly Journal of the American Chemical Society.

Electronic keypad locks long have been fixtures on home security systems and other devices that require a password.

The longest-running search for radio signals from alien civilizations is getting a burst of new data from an upgraded Arecibo telescope, which means the SETI@home project needs more desktop computers to help crunch the data.

Since SETI@home launched eight years ago, the project based at the University of California, Berkeley's Space Sciences Laboratory has signed up more than 5 million interested volunteers and boasts the largest community of dedicated users of any Internet computing project: 170,000 devotees on 320,000 computers.

Yet, new and more sensitive receivers on the world's largest radio telescope in Arecibo, Puerto Rico, and better frequency coverage are generating 500 times more data for the project than before.

A breakthrough in understanding the way atoms move across cell membranes in the human body could pave the way for the development of new treatments for inflammatory diseases such as rheumatoid arthritis.

Scientists at the University of Leeds have identified a previously unknown natural mechanism that opens ion channels – proteins at the cell surface that act as doorways into and out of cells – through the naturally occurring protein thioredoxin.

Ion channels allow movement of ions - electrically charged atoms - across the cell membrane to carry out various functions such as pain transmission, timing of the heart beat, and regulation of blood glucose.

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