A mutation  in a gene called KNSTRN, which is involved in helping cells divide their DNA equally during cell division, is caused by ultraviolet light is likely the driving force behind millions of human skin cancers, according to new research.

Genes that cause cancer when mutated are known as oncogenes. Although KNSTRN hasn't been previously implicated as a cause of human cancers, the research suggests it may be one of the most commonly mutated oncogenes in the world.

A newly developed antifungal named isavuconazole is as effective as voriconazole against invasive mold disease in cancer patients with less adverse effects, according to phase 3 clinical data.

With age, our cells gradually lose their capacity to repair damage, even from normal wear and tear. A new paper discusses why this decline occurs in our skeletal muscle. 

A team led by Dr. Michael Rudnicki, senior scientist at the Ottawa Hospital Research Institute and professor of medicine at the University of Ottawa, found that as muscle stem cells age, their reduced function is a result of a progressive increase in the activation of a specific signaling pathway. Such pathways transmit information to a cell from the surrounding tissue. The particular culprit identified by Dr. Rudnicki and his team is called the JAK/STAT signalling pathway.

The hygiene hypothesis and its cousins, like that rural settings make children microbiologically stronger, now has a study that vegetarian activists are not going to like: sleeping on animal fur in the first three months of life has been linked to reduced risk of asthma.  

Previous studies have suggested that exposure to a wider range of environments from young age could be protective against asthma and allergies - urban settings have not found that to to be so. But in a new study, researchers investigated children from a city environment who had been exposed to animal skin by sleeping on the material shortly after birth. 

Materials made from nano-particles have long been touted as the future viable solar energy production and better touch screens.

The black box between the present and the future of these wonder-materials is organizing the nanoparticles into orderly arrangements. Nanoparticles of magnetite, the most abundant magnetic material on earth, are found in living organisms from bacteria to birds. Nanocrystals of magnetite self-assemble into fine compass needles in the organism that help it to navigate.

The coffee plant has a newly sequenced genome and that can tell scientists what they really want to know about: the evolution of caffeine.

The sequences and positions of genes in the coffee plant show that they evolved independently from genes with similar functions in tea and chocolate, which also make caffeine. Coffee did not inherit caffeine-linked genes from a common ancestor, but instead developed the genes on its own.

Why Coffee?

By Jordan Gaines Lewis, Penn State College of Medicine