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By Michael White | March 10th 2010 03:52 PM | 7 comments | Print | E-mail | Track Comments
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Welcome to Adaptive Complexity, where I write about genomics, systems biology, evolution, and the connection between science and literature,

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Bad habits of ineffective science: Trends in Biochemical Sciences has a piece on Mental inertia in the biological sciences. I'm not quite sure what to make of it, but the piece does contain some interesting thoughts on hot topics vs. important topics:

Almost any scientist wants to work on solving an important problem, but at any given moment, it can be difficult to distinguish the topics that are ‘important’ from those that are ‘hot’. Often the scientific community does not immediately recognize the true significance of the work, and it can remain obscure for many years...

A scientist addressing a truly new problem, a first stager [7], should be prepared to pursue it alone for a time. Moreover, many journals will be reluctant to publish first-stage scientific work that will not immediately bring numerous citations, relegating the work to further obscurity and turning the whole process into a vicious cycle.

And:

The contemporary western approach to scientific funding is very prone to creating long-lasting positive feedbacks or vicious circles of false ‘hot topics’. Funding is distributed among scientific communities: the bigger the community, the greater the likelihood is that it will lobby for its share of funding. Therefore, when a scientist must choose which scientific direction to pursue, they are more likely to select a topic that comes with better funding. Thus, a large community that has assured its funding will become even larger. The increase in community membership within this subfield will lead to more publications and higher numbers of citations. At an extreme, a community could become ‘self-sufficient’, and attempts to challenge it by democratic means would be unlikely to succeed.

My perception is that hot topics in biology typically, while not necessarily the most intellectually important topics in the field, are topics that have been opened up by the development of some new technology that enables scientists to address an old question more comprehensively, or in more detail. Think of live imaging of cells with GFP, microarrays, better DNA sequencing technology, high-throughput protein and metabolite mass spectrometry, cancer genome projects, GWAS, metabolomics, etc. To a large degree, biology today is driven more by new technology, and less by new ideas about biology.

I'm not implying that technologically-driven questions are worthless, but they are frequently centered around issues that have already been widely recognized in the field, sometimes for decades.

Read the feed:


Comments

jtwitten
Perhaps we should rename the SB "Hot Topics" section to "Important Topics", or better yet to "Topics of Significant Import".

Hank
Well, some topics are hot.  Just because a certain segment conscripts an idea and uses it to their own ends does not mean we have to abandon it.

You guys aren't going to stop using evolution and calling everything 'descent with modification' just because the word is used incorrectly in TV commercials either.

jtwitten
Personally, I refer to it as "the DWM theory of evolution" in order to distinguish the evolutionary theory based on the modern synthesis, as opposed to other theories of evolution or "descent with modification", which could also be applied to Lamarckian theories.

Hank
Indeed, we should never go soft on inheritance!

adaptivecomplexity
I don't think I totally agree with the TiBS author that hot topics are generally falsely hot. Some are important, some are not, some are important but not really new ideas, just newly addressable with new technology.
Hot doesn't mean important; it doesn't mean not important.  Important doesn't mean hot, nor does it mean not hot.

Our hot topics section is hot and important.


Mike

This doesn't really go with your arguement but one problem with technology driven research is that there tends to be very little money devoted to tech development. Imagine the NSF or NIH funding the development of cloning or PCR.

adaptivecomplexity
That's true, as I've been told by a colleague who does a lot of tech development, and an NIH program officer telling my about study section responses to tech development proposals.
Still, tech development does happen at a rapid pace - you can get funded if you put your tech development proposal in terms of specific aims that address a biological question. You basically have to gloss over the fact that you're doing tech development.


Mike

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