Clinical Research

New Antifungal Isavuconazole As Effective As Voriconazole With Fewer Adverse Events

A newly developed antifungal named isavuconazole is as effective as voriconazole against invasive mold disease in cancer patients with less adverse effects, according to phase 3 clinical data. ...

Article - News Staff - Sep 7 2014 - 8:00pm

Randomized Phase II Clinical Trial Of Pracinostat Set For Front Line Myelodysplastic Syndrome

Enrollment in a randomized Phase II clinical trial of Pracinostat in combination with azacitidine in patients with previously untreated intermediate-2 or high-risk myelodysplastic syndrome (MDS) has been completed. The multi-center, placebo-controlled, dou ...

Article - News Staff - Sep 8 2014 - 8:01am

Fast Track Designation For Motolimod Immunotherapy In Ovarian Cancer

In 2014, there will be an estimated 22,240 new cases of ovarian cancer in the United States and over 40,000 new cases in the European Union. Ovarian cancer is one of the most lethal gynecologic cancers. Women with recurrent or persistent ovarian cancer rec ...

Article - News Staff - Sep 8 2014 - 10:30am

Clinical Trials Of SYN-004 In For C. Difficile Infections Upcoming

Positive results from its final preclinical toxicology study of SYN-004 have led Synthetic Biologics to get ready for clinical trials of the anti-infective, second-generation product candidate for Clostridium difficile (C. difficile). Synthetic Biologics i ...

Article - News Staff - Sep 9 2014 - 8:00am

RVX-208 Brings 77% Relative Risk Reduction Of Major Adverse Cardiovascular Events For Diabetes Mellitus Patients

In an oral presentation at the 2014 European Society of Cardiology (ESC) Congress in Barcelona, Dr. Jan Johansson, senior vice president of medical affairs at Resverlogix, disclosed that patients with cardiovascular disease (CVD) arising from atheroscleros ...

Article - News Staff - Sep 10 2014 - 7:00am

Keytruda: FDA Approves Melanoma Drug That Uses Immune System To Fight Cancer

The U.S. Food and Drug Administration has approved Keytruda (pembrolizumab), a new immunotherapy drug to treat advanced melanoma after it was tested on more than 600 patients who had melanoma that had spread throughout their bodies. Because so many of the ...

Article - News Staff - Sep 12 2014 - 3:19pm

Merck Discontinues Tecemotide For Stage III Non-Small Cell Lung Cancer

Merck is discontinuing the clinical development program of its investigational MUC1 antigen-specific cancer immunotherapy tecemotide (L-BLP25) as a monotherapy in Stage III non-small cell lung cancer (NSCLC). Tecemotide is an investigational MUC1 antigen-s ...

Article - News Staff - Sep 12 2014 - 7:05pm

UM171: New Molecule Allows For 10X Increase In Adult Stem Cell Transplants

Investigators have announced discovery of a new molecule, the first of its kind, which allows for the multiplication of stem cells in a unit of cord blood. Umbilical cord blood contains adult stem cells used for transplants aimed at curing a number of blo ...

Article - News Staff - Sep 18 2014 - 3:08pm

Uterus Transplant Leads To First Successful Baby Delivery

Seven Swedish women have had embryos reintroduced after receiving wombs from living donors and now one has delivered a healthy and normally developed boy, reveals the case study in The Lancet. The uterus transplantation research project at the University ...

Article - News Staff - Oct 7 2014 - 9:29am

The Obesity Paradox—Seriously?

Obesity is a significant risk factor for the development of a number of diseases, but the first that comes to mind is type 2 diabetes.  ...

Article - Joe Cornicelli - Oct 10 2014 - 1:04pm