Clinical Research

E. Coli: Bacterial Diarrhea Vaccine Candidate Highly Efficacious

Each year, nearly 600,000 children die from severe, dehydrating diarrhea and millions more are hospitalized. Enterotoxigenic Escherichia coli (ETEC) may be the first enteric illness encountered by many infants, and it causes several hundred million cases ...

Article - News Staff - Oct 27 2014 - 10:31am

The Risks And Rewards Of Two Popular Gastric Bypass Procedures

A recent study compared two of the most commonly performed bariatric surgery procedures. There are tradeoffs between the two surgical approaches in potential risks and benefits and so there has been an ongoing debate about which can achieve weight loss, w ...

Article - News Staff - Oct 30 2014 - 9:30am

Beta-Blockers For Some Heart Failure Linked With Improved Survival

Up to 50 percent of patients with heart failure have normal or near-normal ejection fraction, termed heart failure with preserved ejection fraction (HFPEF). The risk of death in HFPEF may be as high as in heart failure with reduced ejection fraction (HFRE ...

Article - News Staff - Nov 16 2014 - 3:27pm

Clinical Trials For Rich Patients Could Help Find Cures For Us All

Overcoming gaps in medical funding. nakrnsm, CC BY By Stephanie Swift, University of Ottawa Disease can affect any person, rich or poor. While your bank balance can’t really protect you from getting sick, it could potentially buy you – and many other pati ...

Article - The Conversation - Dec 29 2014 - 8:30am

Scorpion Venom Could Lead To New Cancer Treatment

Okay, but that's not the way to extract it. fabriceh_com, CC BY-NC-SA By Benjamin Burke, University of Hull In the development of new drugs, taking something from nature and modifying it has been a successful tactic employed by medicinal chemists for ...

Article - The Conversation - Jan 6 2015 - 2:31pm

Fixing 'leaky' Blood Vessels To Combat Severe Respiratory Ailments

Leaky blood vessels in the lung can lead to acute respiratory distress. Shutterstock By Jalees Rehman, University of Illinois at Chicago ...

Article - The Conversation - Jan 18 2015 - 1:30pm

Industry Clinical Trial Results More Likely To Be Disclosed Than Academic Ones

Academics have written a lot of articles claiming their competitors in the private sector selectively publish trials that favor their own interests don't care as much about transparency as academia, but is that really true?  When it comes to investiga ...

Article - News Staff - Mar 11 2015 - 6:43pm

Glucose-Lowering Therapies To Treat Diabetes May Trigger Heart Failure

An examination of clinical trials covering more than 95,000 patients has found that glucose or sugar-lowering medications prescribed to patients with diabetes may pose an increased risk for the development of heart failure in these patients. Heart failure ...

Article - News Staff - Mar 16 2015 - 9:08pm

AstraZeneca's Antibiotic Spin Off

I just came back from Boston and the annual meeting of BAARN – the Boston Area Antibiotic Resistance Network symposium held at the Broad Institute.   The meeting was interesting but the atmosphere was funereal. Many of those losing their jobs with the clos ...

Article - David Shlaes - Mar 20 2015 - 9:05am

Human Respiratory Tissue Model For Toxicity Of Inhaled Pollutants

A 3-dimensional model of human respiratory tissue has been shown to be effective for measuring the impact of chemicals, like those found in cigarette smoke or other aerosols, on the lung.  More effective lab-based tests are required to reduce the need for ...

Article - News Staff - Mar 29 2015 - 11:58am