Previous research has found that soda and coffee consumption are associated with risk of colon cancer. But a new review in the Journal of the National Cancer Institute suggests that drinking even large amounts of coffee and sugar-sweetened, carbonated soft drinks is not linked to the disease.

Earlier studies on subject have reached mixed conclusions. Some found that coffee and tea may lower the risk of cancer, while others found that they could increase the risk. Tea, for instance contains anti-oxidants that in theory help prevent cancer but also has polyamines, which in theory promote cancer. Sugar-sweetened soft drinks are associated with weight gain, obesity, and other conditions that are potential risk factors for colon cancer.

For this study, researchers at the Harvard School of Public Health analyzed data from 13 studies conducted in North America and Europe. Among 731,441 participants in these studies, 5,604 developed colon cancer. Those who drank large amounts of coffee—more than six 8-oz cups a day—were no more likely to develop the disease than those who drank less.

Likewise, those who drank more than 18 oz daily of sugar-sweetened, carbonated beverages had no higher risk of colon cancer. But the authors note that the results for sugar-sweetened carbonated beverages should be interpreted with caution because only 2% of the study population drank more than 18 oz of these beverages daily.

The results were similar regardless of sex, smoking status, alcohol consumption, body mass index, level of physical activity, and location of the tumor.

The authors found a modest association between drinking high amounts of non-herbal tea—more than four 8-oz cups a day—and colon cancer risk. However, they note that very few people in the study drank that much tea and that the association could be due to chance.

"Drinking coffee or sugar-sweetened carbonated soft drinks was not associated with colon cancer risk," the researchers conclude. "However, a modest positive association with higher tea consumption is possible and requires further study."


Citation: Zhang et al., 'Risk of Colon Cancer and Coffee, Tea, and Sugar-Sweetened Soft Drink Intake: Pooled Analysis of Prospective Cohort Studies', Journal of the National Cancer Institute, 2010; doi: 10.1093/jnci/djq107