New research published in Stroke has linked the risk of suffering a stroke to the presence of a certain type of antibody in the immune system. According to the study, researchers may now be able to develop a vaccine that can mobilize the body's own defence against arteriosclerosis and stroke.
The study compared 227 individuals who had suffered stroke over a 13-year period with 445 sex and age-matched controls. After controlling for other risk factors (age, sex, smoking habits, cholesterol levels, diabetes, BMI and blood pressure), they were able to show that low levels (below 30 per cent of average) of PC antibodies correlated with a higher risk of stroke, which in women meant an almost three-fold increase.
The researchers have now advanced the hypothesis that low levels of natural PC antibodies, which can be a condition of a poor immune system – contribute to the development of arteriosclerosis and its consequences, which include stroke.
"We're now examining the possibility of developing new immunological treatments for arteriosclerosis and stroke, either in the form of a vaccine to stimulate the immune defence or immunisation through the injection of antibodies," says co-author Professor Johan Frostegård of the Karolinska Institutet.
Citation: Fiskesund et al., 'Low levels of antibodies against phosphorylcholine predict development of stroke in a population based study from Northern Sweden', Stroke, February 2010; doi: 10.1161/STROKEAHA.109.558742
- PHYSICAL SCIENCES
- EARTH SCIENCES
- LIFE SCIENCES
- SOCIAL SCIENCES
Subscribe to the newsletter
Stay in touch with the scientific world!
Know Science And Want To Write?
- Matter Can Potentially Accelerate The Expansion Of The Universe
- Metal Hip Replacements Implanted Since 2006 More Prone To Failure
- The Number Of My Publications Has Four Digits
- Unique Fragment From Earth’s Formation Returns Home
- Does lower literacy make you a sucker for online health ads?
- Professor Frenkel: Why Shouldn't We Drop Algebra From Our Education System?
- Age reversing drugs from MIT gerontologist available. More to come.
- "Even using Wikipedia, an illustration of the conventional prejudice on the matter energy density..."
- "In Reading University Library there is a most interesting book Felix Klein and Sophus Lie by I..."
- "Correction (will merge this into the article later): Orange dwarf stars have lifetimes of 15 -..."
- "Lobos, after what you say about academia, I still wander why you keep the Harvard Veritas coat..."
- "For a pedagogical introduction to the Friedmann equations, see for instance this set of lectures..."
- Parents' presence at bedside found to decrease neonatal abstinence syndrome severity
- Breastfeeding app shows promise in supporting first-time mothers
- Study shows asthma-related Twitter posts can predict rise in hospital visits
- Mental health diagnoses rise significantly for military children
- Combination of face-to-face and online bullying may pack a powerful punch