For decades, Americans have been told that high blood cholesterol as a result of heavy saturated fat intake causes cardiovascular disease.
As such, Statin drugs are often prescribed to curb
risk by lowering cholesterol. That convention was challenged by a recent paper.
So now what?
Epidemiology is not science the way many assume it is. Epidemiology can show that organic food causes autism so while studies may show a correlation between high cholesterol and cardiovascular disease, that is not a “cause-and-effect” relationship and never was - good luck explaining that to Dr. Oz and numerous media experts before that. “In fact,” according to a new commentary, “if analyzed carefully, there are more studies that disprove the ‘cause and effect’ hypothesis than even come close to proving it.”
The trend of vilifying saturated fats based on flawed research is traced back through the second half of the 20th century, eventually meeting overdue criticism in a 2010 meta-analysis and a 2012 paper contrasting scientific literature with U.S. and European advisory committee guidelines. While saturated fats have been blamed for causing CVD, more recent scientific literature points instead to processed sugars, trans-fats, and starchy/processed high-glycemic carbs as the more likely culprits. “Our nutritional courts,” the authors of a new
Journal of the American College of Nutrition
editorial write, “tried and convicted the wrong man.”
Statin drugs designed to treat high levels of LDL cholesterol began to be widely prescribed in 2001. The commentary authors suggest that “We must treat the patient thoughtfully and choose statin drugs carefully with extreme diligence to avoid unnecessary side effects.”
While these drugs have been linked to lower risk of CVD, numerous studies and clinical trials over the past decade have forced the medical community to re-examine the role of LDL cholesterol in statin use benefits. Some even began to demonstrate that reducing LDL alone was counterproductive in reducing some measures of CVD risk. As such, the authors advocate a more creative and thorough approach to addressing CVD risk, free of the “dogmatic polices” built around saturated fat and cholesterol centric thinking.
The commentary authors invoke legendary physician Francis W. Peabody in support of their convictions, quoted as saying, “The most important aspect in the care of the patient, is the care of the patient.”
Stephen T. Sinatra MD, FACN, Beverly B. Teter PhD, MACN, Jonny Bowden CNS, Mark C. Houston MD, FACN, and Miguel A. Martinez-Gonzalez MD, PhD, MPH, 'The Saturated Fat, Cholesterol, and Statin Controversy: A Commentary', Journal of the American College of Nutrition DOI: 10.1080/07315724.2014.878633
- PHYSICAL SCIENCES
- EARTH SCIENCES
- LIFE SCIENCES
- SOCIAL SCIENCES
Subscribe to the newsletter
Stay in touch with the scientific world!
Know Science And Want To Write?
- On Sexuality, You Weren't Born That Way, Says Paper
- Bubble-wrapped Sponge Creates Steam Using Sunlight
- Reframing Body Weight As Baby Weight May Help Women Handle Pregnancy
- Petition: Let's End Dramatized Reporting Of "Doomsday" Stories - The Vulnerable Get Suicidal
- Stem Cell Therapy Heals Injured Mouse Brain
- Watching Thoughts -- And Addiction -- Form In The Brain
- Post-Doctoral Positions In Experimental Physics For Foreigners
- "i've often wondered https://en.wikipedia.org/wiki/Behavioral_sink ..."
- "Dylan, yes back online now. The Sun, and Moon are visible in all those places, of course, so if..."
- "Tina, I think it's best to try to understand the constellation argument because then you can just..."
- "People worry about a system entering ours and spelling doomsday for us all, however I believe if..."
- " I appreciate your hard work and look forward to any future publications with great interest, thank..."
- Pregnancy-Related Deaths Rising, But Why?
- Fauci: Don’t Make Policy Based on Animal Studies
- Exercise Could Save Your Liver
- Precision Medicine Stands On Imprecise Infrastructure
- Standing with Giants: A Collection of Public Health Essays in Memoriam to Dr. Elizabeth M. Whelan
- RIP Dr. D.A. Henderson, ACSH Trustee Who Helped End Smallpox
- Modelling water uptake in wood opens up new design framework
- First randomized trial shows IVF culture media affect the outcomes of embryos and babies
- Intravenous glyburide treatment may reduce dangerous brain swelling after stroke
- Direct and active parent involvement key to healthy living for kids
- Insulin pill could make diabetes treatment 'ouchless'