High cholesterol levels are considered to be a risk factor not only for cardiovascular disease including stroke, but also for the development of Alzheimer's disease so cholesterol lowering drugs, including statins, developed in recent years may help with both. In addition to the cholesterol reducing effect of statins Amalia Dolga, PhD, of the University of Groningen, The Netherlands, and her co-investigators have demonstrated that statins can protect nerve cells against damage which we know to occur in the brain of Alzheimer's disease patients.

The results are published in the June issue of the Journal of Alzheimer's Disease.

Rearrangements in genomes, genes and exons can result from a glitch in DNA copying that occurs when the process stalls at a critical point and then shifts to a different genetic template, duplicating and even triplicating genes or just shuffling or deleting part of the code within them, said researchers from Baylor College of Medicine in a recent report in Nature Genetics. The report further elucidated the effect of the fork stalling and template switching mechanism involved in some forms of copy number variation.

In England and Wales, the national health statistics in 2007 showed that there were 8,324 death certificates which named Clostridium difficile. This is a bacterium which causes severe diarrhea in humans and animals as the underlying cause of death, a 28% increase from 2006.

Now Janet Nale of the Department of Infection, Immunity and Inflammation is investigating the contributing factors that make Clostridium difficile so aggressive to direct treatment. 

Nale said: “Bacteriophages are viruses that infect bacteria and some can completely change the behaviour of their host bacteria, or affect its ability to cause disease. In some cases, bacteriophages have been shown to convert a mild strain to a severe one.

Differences in growth factor (GF) signaling may cause the poor prognosis in some breast cancer cases. A new study, published in the open access journal BMC Medical Genomics, suggests that some estrogen receptor-positive breast cancers respond poorly to tamoxifen because of increased GF signaling.

Now there's a new reason for the weight-conscious to drink fat free milk at breakfast time, suggests a new study published in the July issue of the American Journal of Clinical Nutrition. Researchers in Australia found that drinking fat free milk in the morning helped increase satiety, or a feeling of fullness, and led to decreased calorie intake at the next meal, as compared with a fruit drink. The milk drinkers ate about 50 fewer calories (or nearly 9% less food) at lunch.

The Earth's mantle, situated under the Earth's crust, is a key area for understanding geological processes but we only come into contact with Earth's circulating layers in the event of earthquakes and volcanic eruptions. It's important to learn more about the characteristics of the Earth's mantle and these characteristics can be portrayed using seismic waves but the techniques used for this purpose still have various shortcomings. Dutch-sponsored research Ebru Bozdag demonstrated this during her doctoral research.