New findings may help ease concerns for women with lupus who are interested in having a child. A new study concludes that most women with lupus whose disease is not very active will have a safe pregnancy. The results are to publish online June 22 in Annals of Internal Medicine.

It was previously suggested that women with lupus avoid pregnancy because of serious complications to their own health and the health of the baby. As more knowledge became available, doctors told women with lupus to wait until symptoms were under control, but until now, it was still uncertain whether this advice was right and whether pregnancy outcomes would be favorable.

In a new study published today in The Veterinary Journal, scientists from the University of Surrey warn about the numerous risks posed to racehorses from the misuse of cobalt chloride, a banned performance-enhancing agent that has been used illegally by trainers in Australia and USA. The team of researchers have uncovered that when excessive levels of the alleged performance-enhancing substance are administered to a horse, it can cause serious cardiovascular issues, potential nerve problems, thickening of the blood and thyroid toxicity. The researchers also pointed to the lack of evidence for enhanced performance in horses and human athletes.

Cancer and type 2 diabetes are two of the most significant public health burdens facing the world today, and currently available data suggests their prevalence is expected to continue to increase. Nut consumption has long been hypothesized to have a role in preventing both of these diseases, but until now evidence has been inconsistent. A new systematic review and meta-analysis published in Nutrition Reviews on June 16 shows that nut consumption is, indeed, associated with a decreased risk of certain types of cancer, but not type 2 diabetes.

A new approach to skin rejuvenation developed at Massachusetts General Hospital (MGH) may be less likely to have unintended side effects such as scarring and altered pigmentation. In the online journal Scientific Reports, an MGH research team reports that treatment with pulsed electric fields - a noninvasive procedure that does not involve the generation of heat - removed skin cells in an animal model without affecting the supporting extracellular matrix, eventually leading to renewal of the skin surface.

Inside the cell, DNA is tightly coiled and packed with several proteins into a structure called "chromatin", which allows DNA to fit in the cell while also preventing genes from being expressed at the wrong time. Guided by a chemical "barcode", specialized effector proteins can bind chromatin and either unwind it or compact further to activate or silence genes. This system has enormous implications for biology and medicine, e.g. cancer research. However, the efficiency of effector-chromatin interactions have been elusive, especially given the weak binding between the two. Tracking these interactions one molecule at a time, EPFL scientists have shown for the first time how a major effector protein speeds up its search for chromatin binding sites pairing up with others of its kind.

A new study led by Vanderbilt University Medical Center investigators found new diagnoses of prostate cancer in the U.S. declined 28 percent in the year following the draft recommendation from the United States Preventive Services Task Force (USPSTF) against routine PSA screening for men. The new research, led by first author Daniel Barocas, M.D., MPH, assistant professor of urological surgery and medicine, was posted online in the June 15 issue of The Journal of Urology in advance of publication.