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Various drugs companies have tried to produce antibodies that bind to the type 1 insulin-like growth factor, or IGF-1, receptor on the cell surface, which has a critical part to play in the development of cancer - but have had little success.

Understanding more about how these antibodies work may help explain why only some cancer patients are helped by IGF-1 blockers during clinical tests. 

New research found a more than four-fold increase in the incidence of breast cancer in women with neurofibromatosis-1 (NF1), which adds to evidence that women with this rare genetic disorder may benefit from early breast cancer screening (mammograms) beginning at age 40, and manual breast exams as early as adolescence.

The European Commission has approved  Abbott's HUMIRA® (adalimumab) for the treatment of pediatric patients aged 6 to 17 years with severe active Crohn's disease (CD) who failed, are intolerant to, or have contraindications to conventional therapy. 

A global poll of executives found  that e-commerce giant Amazon is more admired than its Californian rival on all major supply chain attributes - except innovation. 

Amazon is more respected than Apple for supply chain excellence and the Seattle-based retailer also came out top on three of the four supply chain attributes that survey participants were asked to rate the two companies on - agility, collaboration and execution - according to research published today by SCM World, the leading global community of supply chain practitioners.  Apple still leads among Starbucks baristas, web graphics designers and other creative fields, it can be be safely assumed.

Of about 250,000 women enrolled in an integrated healthcare delivery system, increased CT utilization between 2000 and 2010 could mean an increase in the risk of breast cancer for certain women, including younger patients and those who received repeat exams. According to the study presented today at the annual meeting of the Radiological Society of North America (RSNA), nuclear medicine examinations may also contribute to increased breast cancer risk. 

CT uses ionizing radiation in the form of X-rays to produce cross-sectional images of the body. In nuclear medicine imaging, a radiopharmaceutical—a compound that includes a small amount of a radioactive material—is delivered inside the body to help visualize internal organs.

A community of bacteria that survives in a dark, salty and sub-freezing environment has been discovered beneath nearly 20 meters of ice in one of Antarctica's most isolated lakes.

Lake Vida, the largest of several unique lakes found in the McMurdo Dry Valleys, contains no oxygen, is mostly frozen and possesses the highest nitrous oxide levels of any natural water body on Earth. A briny liquid that is approximately six times saltier than seawater percolates throughout the icy environment that has an average temperature of minus 8 degrees Fahrenheit.