New research led by investigators at Memorial Sloan-Kettering Cancer Center (MSKCC) identifies three genes that specifically mediate the metastasis, or spread, of breast cancer to the brain and illuminates the mechanisms by which this spread occurs. The study was published online today in Nature. 

According to the study, COX2 and HB-EGF — genes that induce cancer cell mobility and invasiveness — were found to be genetic mediators in the spread of breast cancer to the brain. A third gene, ST6GALNAC5, was shown to provide cancer cells with the capability of exiting the blood circulation and passing through the blood-brain barrier to enter the brain tissue. 

Children who can stay focused and don't sweat the small stuff have a better shot at good health in adulthood -- especially girls, according to findings reported in the May issue of Health Psychology.

A detailed analysis of the feet of Homo floresiensis, the miniature hominins who lived on a remote island in eastern Indonesia until 18,000 years ago, may help settle a question hotly debated among paleontologists: how similar was this population to modern humans? A new research paper in Nature  may help answer this question.

While the so-called "hobbits" walked on two legs, they say, several features of their feet were so primitive that their gait was not efficient.

A new study from Northwestern University shows what many mothers already know: their babies are a lot smarter than others may realize.

Though only five months old, the study's cuties indicated through their curious stares that they could differentiate water in a glass from solid blue material that looked very much like water in a similar glass. 

The finding that infants can distinguish between solids and liquids at such an early age builds upon a growing body of research that strongly suggests that babies are not blank slates who primarily depend on others for acquiring knowledge. That's a common assumption of researchers in the not too distant past.

Most people know Edwin Hubble as a famed astronomer, the namesake of the orbiting Hubble Space Telescope (HST).  Most probably don't know he also starred as a forward on the University of Chicago Maroons' Big Ten-champion basketball teams in the early part of the 20th century.  

As an astronomer, Hubble showed that galaxies besides our own existed in the universe, and that the universe is expanding. These findings formed the cornerstone of the Big Bang theory of the universe's origin and opened the field of cosmology.  As a basketball player, the 6-foot-2 Hubble was a member of Chicago teams that posted records of 24-2 in 1907-08 and 10-3 in 1908-09.

Toddlers with autism appear more likely to have an enlarged amygdala, a brain area associated with numerous functions, including the processing of faces and emotion, according to a report in the May issue of Archives of General Psychiatry. In addition, this brain abnormality appears to be associated with the ability to share attention with others, a fundamental ability thought to predict later social and language function in children with autism.