University of Cincinnati researchers say they have discovered a new therapy for transplant patients; targeting the antibody-producing plasma cells that can cause organ rejection.  Steve Woodle, MD, and colleagues found that a cancer drug. bortezomib, that is used to treat multiple myeloma, or cancer of the plasma cells, is also effective in treating rejection episodes caused by antibodies that target transplanted kidneys and reversing rejection episodes that did not respond to standard therapies.

B-lymphocytes, or B cells, play a large role in the humoral immune response by making immune proteins that attack transplanted organs.

As the party season approaches, a timely reminder of the issues surrounding the binge drinking culture are again highlighted by research into 'young people and alcohol' a team lead by Professor Christine Griffin, at the University of Bath. The research, funded by the Economic and Social Research Council (ESRC) suggests several considerations for future policy. 

A British company says they have a solution to the over 22,000 tons of hazardous waste that ends up in UK landfills annually from Alkaline batteries that are thrown away after being used in toys and gadgets, creating a toxic problem for hundreds of years.

Moixa Energy's award winning USBCELL re-usable batteries could help reduce this, they say, as they can be re-used hundreds of times by re-charging in USB ports on desktops, laptops or games consoles, saving consumers from money and helping the planet. USBCELLs were recently a Good Housekeeping consumer awards finalist and in September won the Barclays Commercial 'Green Leaders in Business' award.

During an autoimmune disease, the endogenous defence system (the immune system) loses the ability to distinguish between "self" and "foreign".     As a consequence, the immune system directs its defense against itself, with fatal consequences.

In the case of multiple sclerosis, a chronic, inflammatory autoimmune disease, the immune system attacks the protective layer encapsulating the nerve fibres: This protective layer formed by myelin works like insulation for electrical cables. If the insulation is damaged, the nerves can no longer transmit messages effectively. 

Artificial bone marrow that can continuously make red and white blood cells has been created in a University of Michigan lab.   This development could lead to simpler pharmaceutical drug testing, closer study of immune system defects and a continuous supply of blood for transfusions.

The substance grows on a 3-D scaffold that mimics the tissues supporting bone marrow in the body, said Nicholas Kotov, a professor in the U-M departments of Chemical Engineering; Materials Science and Engineering; and Biomedical Engineering.

The marrow is not made to be implanted in the body, like most 3-D biomedical scaffolds. It is designed to function in a test tube.

JetBrains, creators of intelligent and innovative productivity-enhancing tools for software developers, have announced the Beta version of their new product - Meta Programming System, or MPS. Meta Programming System is a brand new concept of software development environment implementing the Language Oriented Programming paradigm. After several years of research and development, JetBrains has released its Beta version now, targeting 1.0 for early 2009.

Meta Programming System is an environment for professional software developers to create new custom languages, extend existing languages, and use them to develop programs. MPS is also an instrument for creating Domain Specific Languages (DSLs).