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Opioid Addicts Are Less Likely To Use Legal Opioids At The End Of Their Lives

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Throughout the overlooked depths of Lake Michigan and other Great Lakes, a small but important animal is rapidly disappearing.

Until recently, the animal - a shrimplike, energy-dense creature called Diporeia - was a major food source for commercially important species like lake whitefish and many prey fish upon which salmon, trout and walleye rely.

Scientists are employing new research methods in a quest to explain their population freefall, which threatens to negatively affect the Lakes' ecosystems and $4 billion sport fishing industry, said Purdue University researcher Marisol Sepúlveda.

Would you like a side of food poisoning with that salad?

Salmonella can infect plant cells and successfully evade all the defense mechanisms of plants so cleaning the surfaces of raw fruits and vegetables, e.g. by washing, is not sufficient to protect against food poisoning, according to a study published today.

The results of the project are based on a model plant, which also represents the ideal basis for future development work on treatment and testing systems in the area of food safety.

1.5 billion (!) cases of food poisoning are caused by Salmonella bacteria each year (World Health Organisation). If the bacteria survive particularly well in a person, they can even infect intestinal cells and persist for longer. Previously, the only known sources of infection were infected meat products and plants that had come into contact with contaminated water.

Amyloid deposits in tissues and organs are linked to a number of diseases, including Alzheimer’s, Parkinson’s, type II diabetes, and prion diseases such as BSE. However, amyloids are not just pathological substances; they have potential as a nanomaterials.

Amyloid fibrils are bundles of highly ordered protein filaments made of ladder-like strands and can be several micrometers long.

In cross-section, amyloids appear as hollow cylinders or ribbons. Although amyloid fibrils are proteins, they more closely resemble synthetic polymers (plastics) than the usual globular proteins. Amyloids can display amazing mechanical properties similar to spider silk. Spider silk is, by weight, significantly stronger than steel and can be stretched to many times its original length without tearing — properties that have not been reproducible with synthetic fibers.

Lusi, the world’s fastest-growing mud volcano, is collapsing and could subside to depths of more than 140 meters with consequences for the surrounding environment, according to new research.

As the second anniversary (May 29) of the eruption on the Indonesian island of Java approaches, scientists have also found that the center of the volcano is collapsing by up to three meters overnight.

Such sudden collapses could be the beginning of a caldera - a large basin-shaped volcanic depression - according to the research team, from Durham University UK, and the Institute of Technology Bandung, in Indonesia.

Dozens of studies show collagen repair is possible and demonstrate why three types of available skin treatments, topical retinoic acid, carbon dioxide laser resurfacing and injections of cross-linked hyaluronic acid, are effective.

University of Michigan scientists draw on dozens of studies since the early 1990s to explain why these treatments all improve the skin’s appearance – and its ability to resist bruises and tears – by stimulating new collagen. Collagen is a key supporting substance, plentiful in young skin, that’s produced in the sub-surface layer of skin known as the dermis. The findings show that the breakdown of the dermis’ firm, youthful structure is a very important factor in skin aging – a much more straightforward thing to fix than genetic factors that others theorize may be involved.

“Fibroblasts are not genetically shot,” says John J. Voorhees, M.D., F.R.C.P., chair of the Department of Dermatology at the University of Michigan Medical School and the article’s senior author. Fibroblast cells in the skin are the key producers of collagen.

Researchers at The University of Nottingham have taken some important first steps to creating a synthetic copycat of a living cell.

Dr Cameron Alexander and PhD student George Pasparakis in the have used polymers — long-chain molecules — to construct capsule-like structures that have properties mimicking the surfaces of a real cell.

In work published as a 'VIP paper' in the journal Angewandte Chemie International Edition, they show how in the laboratory they have been able to encourage the capsules to 'talk' to natural bacteria cells and transfer molecular information.