A study published in Cancer Prevention Research identifies components of black raspberries with chemopreventive potential. Researchers at the Ohio State Comprehensive Cancer Center found that anthocyanins, a class of flavonoids in black raspberries, inhibited growth and stimulated apoptosis in the esophagus of rats treated with an esophageal carcinogen.
Gary D. Stoner, Ph.D., a professor in the department of internal medicine at Ohio State University, and his team of researchers fed rats an anthocyanin-rich extract of black raspberries and found that the extract was nearly as effective in preventing esophageal cancer in rats as whole black raspberries containing the same concentration of anthocyanins. This study demonstrates the importance of anthocyanins as preventive agents in black raspberries and validated similar in vitro findings. It is among the first to look at the correlation between anthocyanins and cancer prevention in vivo.
"Our data provide strong evidence that anthocyanins are important for cancer prevention," said Stoner.
Stoner and his colleagues have conducted clinical trials using whole berry powder, which has yielded some promising results, but required patients to take up to 60 grams of powder a day. "Now that we know the anthocyanins in berries are almost as active as whole berries themselves, we hope to be able to prevent cancer in humans using a standardized mixture of anthocyanins," said Stoner.
"The goal is to potentially replace whole berry powder with its active components and then figure out better ways to deliver these components to tissues, to increase their uptake and effectiveness. Ultimately, we hope to test the anthocyanins for effectiveness in multiple organ sites in humans," said Stoner.
- PHYSICAL SCIENCES
- EARTH SCIENCES
- LIFE SCIENCES
- SOCIAL SCIENCES
Subscribe to the newsletter
Stay in touch with the scientific world!
Know Science And Want To Write?
- Doomsday Dashboard Makes Tracking The Apocalypse Convenient
- Intellectually Gifted Kids And Learning Disabilities Often Go Hand In Hand
- Confirmation Bias: Why The Moon Gets Blamed For A Lot
- High-Intensity Exercise Is Best Before That High Fat Meal
- Urine Is Not Really Sterile
- Another One Bites The Dust - WW Cross Section Gets Back Where It Belongs
- Men Who Eat Produce That Usually Has Higher Pesticide Residues May Have Lower Semen Quality
- "Could we have a new poster child for junk science? Ladies and gentlemen, we have a correlation..."
- "The hull design is nearly the same today as it was back then because aerodynamics haven't changed..."
- "I think if anything Soyuz would be more sensitive. It is a late 60's design with minor updates..."
- "Agreed, mesons are bosons and hadrons...."
- "I applaud Science 2.0 for bringing this study to light for the public. I perform nerve decompression..."
- Counter-intuitive: Generous welfare benefits make people more likely to want to work, not less
- BHPI: New drug stalls estrogen receptor-positive cancer cell growth and shrinks tumors
- The bacterial genetic pathway reason you may stink
- Eating fruits and vegetables with high pesticide residues linked to poor semen quality
- Temperature-sensitive engineering from nature: From tobacco to cyberwood