A study published in Cancer Prevention Research identifies components of black raspberries with chemopreventive potential. Researchers at the Ohio State Comprehensive Cancer Center found that anthocyanins, a class of flavonoids in black raspberries, inhibited growth and stimulated apoptosis in the esophagus of rats treated with an esophageal carcinogen.
Gary D. Stoner, Ph.D., a professor in the department of internal medicine at Ohio State University, and his team of researchers fed rats an anthocyanin-rich extract of black raspberries and found that the extract was nearly as effective in preventing esophageal cancer in rats as whole black raspberries containing the same concentration of anthocyanins. This study demonstrates the importance of anthocyanins as preventive agents in black raspberries and validated similar in vitro findings. It is among the first to look at the correlation between anthocyanins and cancer prevention in vivo.
"Our data provide strong evidence that anthocyanins are important for cancer prevention," said Stoner.
Stoner and his colleagues have conducted clinical trials using whole berry powder, which has yielded some promising results, but required patients to take up to 60 grams of powder a day. "Now that we know the anthocyanins in berries are almost as active as whole berries themselves, we hope to be able to prevent cancer in humans using a standardized mixture of anthocyanins," said Stoner.
"The goal is to potentially replace whole berry powder with its active components and then figure out better ways to deliver these components to tissues, to increase their uptake and effectiveness. Ultimately, we hope to test the anthocyanins for effectiveness in multiple organ sites in humans," said Stoner.
- PHYSICAL SCIENCES
- EARTH SCIENCES
- LIFE SCIENCES
- SOCIAL SCIENCES
Subscribe to the newsletter
Stay in touch with the scientific world!
Know Science And Want To Write?
- The BPA Paradox – Too Many Studies?
- Part I: Bee Deaths Mystery Solved? Neonicotinoids (Neonics) May Actually Help Bee Health
- 3X Saturated Fat In The Diet Doesn't Increase It In Blood
- Is Religion A Consolation Worth Having?
- Microwave Electron Guns: A Field-Emission Plug-And-Play Solution
- Mystery Virus That Turned Starfish Into Goo Identified
- GMO Labels Are Good For The $105 Billion Organic Industry - But No One Else
- "Hi PH,no, the topic is really a different one... Naturalness in fundamental physics has nothing..."
- "Right, that's a sort of typo - I confuse the two numbers often.T...."
- "Glad to see I wasn't the only one who thought these authors were trying to fight against corporations..."
- "I am a drug abuse researcher, although I am trying to get away from it, but I disagree with point..."
- "It's not the belief in God (or gods) that leads people to commit atrocities against each other..."
- Clipping proteins that package genes may limit abnormal cell growth in tumors
- Investigational drug reduces high potassium levels in chronic kidney disease patients
- Study: Doubling saturated fat in the diet does not increase saturated fat in blood
- Women with serious mental illness less likely to receive cancer screenings
- Only half of patients take their medications as prescribed