Is sleep essential? The answer seems obvious, since we all have to do it, but to a sleep scientist, the question of what constitutes sleep is so complex that scientists are still trying to define the essential function of something we do every night.
The search for the core function of sleep can seem as elusive as the search for the mythological phoenix, says Chiara Cirelli, an associate professor of psychiatry at the University of Wisconsin School of Medicine and Public Health in Madison.
Some scientists argue that sleep is merely a way to impose a quiet, immobile state (rest), and isn't important by itself in mammals and birds. This is the so-called "null hypothesis," and Cirelli and co-author Giulio Tononi reject it.
So there you have it.
"We don't understand the purpose of sleep, but it must be important because all animals do it," Cirelli says. There's no clear evidence of an animal species that doesn't sleep, she says. Even the dolphin—which is sometimes held up as an animal that doesn't sleep because it moves continuously—will show "unihemispheric sleep" with one eye closed and one half its brain showing the slow waves characteristic of deep sleep.
"The very fact that dolphins have developed the remarkable specialization . . ., rather than merely getting rid of sleep altogether, should count as evidence that sleep must serve some essential function and cannot be eliminated," Cirelli says.
She also argues that sleep is strictly regulated by the brain, because sleep deprivation is followed by a rebound, in which the sleep-deprived animal either sleeps longer, or spends more time in the deeper sleep characterized by large slow brain waves.
Prolonged sleep deprivation has been shown to kill rats, flies and cockroaches. Humans who have a genetic insomnia can also die. In less extreme cases, sleep deprivation affects cognitive function in animals ranging from flies to rodents. Rats kept awake will engage in "micro-sleep" episodes, and sleep-deprived humans tend to fall asleep even in the most dangerous circumstances.
Because it is universal, tightly regulated, and cannot be lost without serious harm, Cirelli argues that sleep must have an important core function. But what?
"Sleep may be the price you pay so your brain can be plastic the next day," Cirelli and Tononi say.
Their hypothesis is that sleep allows the brain to regroup after a hard day of learning by giving the synapses, which increase in strength during the day, a chance to damp down to baseline levels. This is important because the brain uses up to 80 percent of its energy to sustain synaptic activity.
Sleep may also be important for consolidating new memories, and to allow the brain to "forget" the random, unimportant impressions of the day, so there is room for more learning the next day. This could be why the brain waves are so active during certain periods of sleep.
"While there may still be no consensus on why animals need to sleep, it would seem that searching for a core function of sleep, particularly at the cellular level, is still a worthwhile exercise," she concludes.
Citation:Cirelli C, Tononi G (2008) Is sleep essential? PLoS Biol 6(8): e216. doi:10.1371/journal.pbio.0060216
- PHYSICAL SCIENCES
- EARTH SCIENCES
- LIFE SCIENCES
- SOCIAL SCIENCES
Subscribe to the newsletter
Stay in touch with the scientific world!
Know Science And Want To Write?
- New Tractor Beam Can Repel And Attract
- Researchers Created A Laser Bullet To See What It Would Look Like - And Here It Is
- Erupting Bardarbunga Volcano In Iceland Sits On A Massive Magma Hot Spot
- Climate Change Caused By The Ocean
- Home, Workplace, Tomb – Fury And The Reality Of The World War II Tank
- Blood Vessel Transplant From Own Stem Cells - Now In A Week
- Germany’s Green Energy Gamble Could Really Use Some Vorsprung Durch Technik
- "Well stated dersu. I add that the big problem is we still don't have a working model of the brain..."
- "Underage drinking is declining in the US - has been for about a decade. Don't easily available..."
- "A lower range of likely values for climate sensitivity, a larger role from the oceans, if..."
- "But do you understand that these futuristic machines may also be used to study the property of..."
- "Both in this article and the press release from ASU Biodesign are carefully worded allusion to..."
- How to sell a toxic pesticide the smart way–call it organic
- Leftist dystopia? Anti-technology fever animates opposition to GMOs and other ‘disruptive’ technologies
- CDC faced a nearly impossible balancing act with Ebola, and failed
- Why Chobani reversed course, making yoghurt only from milk from cows not fed GMO grain
- Monterey, California, hotbed of anti-GMO activism, home to new GMO corn farm
- Evolution is sometimes messy or even outright ridiculous