Trousers have to be tried on – the variation between size labeling and actual clothing size is huge. This is shown by the report "Large? Clothing sizes and size labeling", which looks at the relationship between clothing sizes and the actual clothing measurements as well as consumers' views on and experiences of this.

The study of epigenetics in psychiatry promises several key advances, as noted by Eric J. Nestler, M.D., Ph.D., a Deputy Editor for Biological Psychiatry and an expert in this field.

First, it enables, for the first time, direct study of mechanisms controlling transcription, the process of expressing the genetic information coded within DNA, in the brains of behaving animals as well as in brain tissue from humans studied at autopsy.

Second, some epigenetic changes in the brain are likely to be extremely long-lived, and thereby represent potential mechanisms by which life events, or psychotropic drugs or even psychotherapy, can produce stable, long-lasting changes in behavior.

Originating from Africa, India, and the Middle East, frankincense oil has been found to have many medicinal benefits. Now, an enriched extract of the Somalian Frankincense herb Boswellia carteri has been shown to kill off bladder cancer cells. Research presented in the open access journal, BMC Complementary and Alternative Medicine, demonstrates that this herb has the potential for an alternative therapy for bladder cancer.

Bladder cancer is twice as common in males as it is in females. In the US, bladder cancer is the fourth most common type of cancer in men, whilst in the UK it is the seventh most common cause of death amongst males.

CAMBRIDGE, Mass.--A rising tide is said to lift all boats. Rising global temperatures, however, may lead to increased disparities between rich and poor countries, according to a recent MIT economic analysis of the impact of climate change on growth.

After examining worldwide climate and economic data from 1950 to 2003, Benjamin A. Olken, associate professor in the Department of Economics, concludes that a 1 degree Celsius rise in temperature in a given year reduces economic growth by an average of 1.1 percentage points in the world's poor countries but has no measurable effect in rich countries.

Olken says his research suggests higher temperatures will be disproportionately bad for the economic growth of poor countries compared to rich countries.

(PHILADELPHIA) A novel signaling pathway plays a significant role in the production of aldosterone, a hormone that promotes heart failure after a myocardial infarction, according to a study conducted by Thomas Jefferson University researchers.

The findings, which will be published online this week in Proceedings of the National Academy of Sciences, show that aldosterone production is mediated by a protein called beta-arrestin-1. Beta-arrestin-1 binds to angiotensin II receptors when they are activated by angiotensin II.

One of the small regulatory molecules, named microRNA-125b, is a novel regulator of p53, an important protein that safeguards cells against cancers, Singapore and U.S. scientists report in the March 17, 2009 issue of the journal Genes & Development.

The scientists found that during embryonic development, this microRNA keeps the level of p53 low to avoid excessive cell death.

But, if the DNA is damaged, the microRNA level is reduced to allow an increase in p53, which eliminates damaged cells and thus prevents tumor formation.

The research was conducted with zebrafish.