COPPELL, Texas, April 22 /PRNewswire/ --

- International success leads to 11th country in Mannatech's global expansion

Mannatech, Incorporated (Nasdaq: MTEX), a developer and provider of dietary supplements and skin care solutions, announced today the launch of operations in South Africa. A continuation of Mannatech's success in international expansion, the South Africa opening marks the 11th country where the company does business.

http://www.mannatech.com

"We're anxiously looking forward to introducing our proprietary and patented products in South Africa," said Mannatech's President and CEO Terry Persinger. "Years ago, South Africa was the first country to grant a patent for the technology related to the formulation of Mannatech's flagship product, Ambrotose complex."

South Africa's rich legacy of using nature's biodiversity to address wellness aligns well with Mannatech's emphasis on natural ingredients.

Mannatech is offering a full range of dietary and glyconutritional products in South Africa. Among these products is the Optimal Health System, which is comprised of Ambrotose complex; PhytoMatrix -- a revolutionary and unique supplement containing natural vitamin complexes, standardized levels of plant-derived minerals and a blend of fully stabilized phytonutrients; Ambrotose AO -- a proprietary antioxidant; and PLUS -- an herbal-amino acid that supports endocrine health.

http://www.exploremannatech.com/optimalhealth-products.htm

About Mannatech

Mannatech, Incorporated, is a global wellness solutions provider of innovative, high-quality, proprietary nutritional supplements, topical and skin care products, and weight management products sold through independent associates and members located in the United States and the international markets of Canada, Australia, the United Kingdom, Japan, New Zealand, the Republic of Korea, Taiwan, Denmark, Germany and South Africa.

Please Note: This release contains "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, as amended, Section 21E of the Securities Exchange Act of 1934, as amended, and the Private Securities Litigation Reform Act of 1995. These forward-looking statements generally can be identified by use of phrases or terminology such as "intend" or other similar words or the negative of such terminology. Similarly, descriptions of Mannatech's objectives, strategies, plans, goals or targets contained herein are also considered forward-looking statements. Mannatech believes this release should be read in conjunction with all of its filings with the United States Securities and Exchange Commission and cautions its readers that these forward-looking statements are subject to certain events, risks, uncertainties, and other factors. Some of these factors include, among others, Mannatech's inability to attract and retain associates and members, increases in competition, litigation, regulatory changes, and its planned growth into new international markets. Although Mannatech believes that the expectations, statements, and assumptions reflected in these forward-looking statements are reasonable, it cautions readers to always consider all of the risk factors and any other cautionary statements carefully in evaluating each forward-looking statement in this release, as well as those set forth in its latest Annual Report on Form 10-K and Quarterly Report on Form 10-Q, and other filings filed with the United States Securities and Exchange Commission, including its current reports on Form 8-K. All of the forward-looking statements contained herein speak only as of the date of this release.

Contact Information: Gary Spinell, Vice President Investor Relations +1-972-471-6512 pr@mannatech.com Corporate website: http://www.mannatech.com

Web site: http://www.mannatech.com

Gary Spinell, Vice President, Investor Relations of Mannatech, Incorporated, +1-972-471-6512, pr@mannatech.com ; Photo: http://www.newscom.com/cgi-bin/prnh/20051213/MANNATECHLOGO, AP Archive: http://photoarchive.ap.org, PRN Photo Desk, photodesk@prnewswire.com