Researchers have evaluated the safety and reliability of the existing targeted gene correction technologies, and successfully developed a new method, TALEN-HDAdV, which could significantly increased gene-correction efficiency in human induced pluripotent stem cell (hiPSC). 

The combination of stem cells and targeted genome editing technology provides a powerful tool to model human diseases and develop potential cell replacement therapy. Although the utility of genome editing has been extensively documented, but the impact of these technologies on mutational load at the whole-genome level remains unclear.

Though drones have gotten a bad rap lately due to an overzealous American government obsessed with using technology to control the message, they will soon have benefits in the private sector outside bird's eye views of fireworks.

Take photography. Lighting is crucial in photographs and film-making but lights are cumbersome and time-consuming to set up, and out of doors can be prohibitively difficult to position them where, ideally, they ought to go.

Researchers at MIT and Cornell University hope to change that by providing photographers with squadrons of small, light-equipped autonomous robots that automatically assume the positions necessary to produce lighting effects specified through a simple, intuitive, camera-mounted interface.

Though England football fans stopped singing "Three Lions" after the second game of the opening round at World Cup 2014, there is still hope to bring back hardware: in robotics.

The University of Hertfordshire’s robot football team, the ‘Bold Hearts’, is set to fly out to Brazil next week to compete in the 2014 RoboCup robotics world championship, taking place in João Pessoa, Brazil, 19 – 24 July 2014.

Imagine getting this text message when you are at the pub tonight: "Looking forward to seeing you at 2 AM - General Hospital".

Creepy, but it may work. 

Young adults who screened positive for a history of hazardous or binge drinking reduced their binge drinking by more than 50 percent after receiving mobile phone text messages following a visit to the emergency department, according to a new paper. 

One possible future in the therapy of children with cognitive and motor-skill disabilities could involve the popular Finnish game "Angry Birds" - and a robot.

Georgia Institute of Technology recently paired a small humanoid robot with an Android tablet and then asked kids to teach the robot how to play the game, dragging their finger on the tablet to whiz the bird across the screen.

The robot watches what happens and records "snapshots" in its memory. It notices where fingers start and stop, and how the objects on the screen move according to each other, while constantly keeping an eye on the score to check for signs of success. 

For good or bad, the Affordable Care Act - Obamacare - is making electronic health records ubiquitous.That means the sheer quantity of clinical data that will become available for research and analytic purposes will skyrocket. The possibility for clinical analytics to analyze large quantities of data for the purpose of gleaning insights has the potential to improve the value of patient care. Science knows all about such big data. It will be good to see if new approaches for health care can benefit research also.  

There are 10 proteins in the blood which can predict the onset of Alzheimer's and that means there may be a blood test for the disease on the horizon.

Proteomics company Proteome Sciences plc and King's College London examined over individuals from three international studies. Blood samples from a total of 1,148 individuals (476 with Alzheimer's disease; 220 with 'Mild Cognitive Impairment' (MCI) and 452 elderly controls without dementia) were analyzed for 26 proteins previously shown to be associated with Alzheimer's disease. A sub-group of 476 individuals across all three groups also had an MRI brain scan. 

The PandaX experiment of China is located in a deep underground laboratory, shielded by 2,400 meters of low radioactive rocks to provide protection for PandaX against cosmic muons. It began operation in March but has no results yet, so they published a technical design report to show the Chinese government they are doing something.

Medicine is advancing rapidly and it always has risks, but in early going the risks are going to be greater. A paper found that the risk of patient harm increased two-fold in 2006, the year when teaching hospitals nationwide embraced the pursuit of minimally invasive robotic surgery for prostate cancer.

Researchers at the Center for Research and Advanced Studies (Cinvestav) in Mexico have developed a cDNA microarray chip that allows detection of the RNA strand of the dengue fever virus.

The genetic information pinpoints the exact serotype of malaria that an infected person or mosquito is carrying  and allows analysis of the complementary strand of DNA (cDNA) obtained from the dengue fever virus being carried by the infected patient. The cDNA is covalently linked to a slide (substrate) that can be a glass or paper.