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Whole genome sequencing of a family - predicting the future?

Whole genome sequencing of a family - predicting the future?

Sep 16 2011 | comment(s)

Although genetic sequencing sounded exciting - I'll send you a tube full of spit, you tell me what diseases I'm going to get - the reality was less thrilling, and less useful. There are diseases with very specific and even single mutations, but the big 'uns - cardiovascular disease, cancer, diabetes - are more tangled and complicated than trying to find a redeeming quality in a Kardashian. 
Even with the ethical dilemmas involved and murky predictability, I still think the potential is fascinating. A story on the whole genome of a family of four, and how the research predicted the daughter's risk of blood clots and a warning against possible preventive pharmacological intervention, caught my eye.
Tommaso Dorigo And Peter Woit at TED Conference in Flanders

Tommaso Dorigo And Peter Woit at TED Conference in Flanders

Sep 15 2011 | comment(s)

September 24th 2011 at the Flemish Opera in Flanders, Science 2.0 columnist (and LHC physicist and Tevatron physicist and educator) Tommaso Dorigo and Peter Woit, Senior Lecturer in the Mathematics department at Columbia University and scribe at Not Even Wrong, will be discussing the Higgs for the scientifically curious audience at TEDx.
Explaining The Higgs At TEDx

Explaining The Higgs At TEDx

Sep 15 2011 | comment(s)

In two weeks I will be talking at TEDx Flanders, in the magnificent theatre of the Flemish Opera of Antwerp, Belgium. I can't wait, of course, and I have prepared a presentation which is hopefully going to be digestible, but I would hope enjoyable, for the thousand total outsiders who will listen to it in-between a couple dozen other extremely interesting performances and talks. The program is indeed quite diverse and exciting, and the event will last the full day of Saturday, Sept. 24th.
Kepler-16b Double Sunset: First Planet Orbiting Two Stars Confirmed

Kepler-16b Double Sunset: First Planet Orbiting Two Stars Confirmed

Sep 15 2011 | comment(s)

A terrific scene in "Star Wars" - when "Star Wars" universe was still good(1) - was the double sunset on Tatooine.  It wasn't the first time it was done but the graphics in "Star Wars" were light years ahead of its competition.  Well, parsecs ahead of their time, if you understand physics the way George Lucas did (2).

We may now get to think about what it's like for real, though no one lives on the newly discovered cold and gaseous planet, Kepler-16b in the Kepler-16 system,  which orbits two stars.
Research Shows Beer Runs Are Good For You

Research Shows Beer Runs Are Good For You

Sep 15 2011 | comment(s)

Here’s a question for your buddies at the next golf outing or bowling league night: Are we more active because we drink more or do we drink more because we’re more active? Recent research showed that there is a correlation between the two, but could not offer a solid reason.

Either way, another study claims the combination of moderate alcohol use and exercise will help our hearts more than just choosing one over the other.
Professors Offer $10K For Story That HPV Vaccine Caused Retardation

Professors Offer $10K For Story That HPV Vaccine Caused Retardation

Sep 15 2011 | comment(s)

Politicians throw out a lot of anecdotes, especially if it is one told by a constituent or potential voter, so Minnesota Rep. Michele Bachmann throwing forth a story told to her that the HPV vaccine caused a child's retardation would be just that, a story. Even it if is a just-so story.

Except she's a Republican. And so academics have offered $10,000 for the source of that story.
Acherontisuchus Guajiraensis: Prehistoric Giant Crocodile Versus The World's Largest Snake

Acherontisuchus Guajiraensis: Prehistoric Giant Crocodile Versus The World's Largest Snake

Sep 15 2011 | comment(s)

A giant crococile versus a giant snake in a Colombian coal mine? It sounds even more awesome than "Mega Shark Versus Giant Octopus", except the real life version does not have Debbie Gibson.

An ancient crocodile relative, a dyrosaurid now named Acherontisuchus guajiraensis, likely gave the world's largest snake a tussle or two. In Palaeontology, University of Florida researchers describe the new 20-foot extinct species which was discovered in the same Colombian coal mine as Titanoboa cerrejonensis, the world's largest snake.
Synthetic Yeast Chromosomes

Synthetic Yeast Chromosomes

Sep 15 2011 | comment(s)

A research team at John Hopkins Medical Institutions has introduced synthetic chromosomes into yeast (Saccharomyces cerevisiae, see figure 1), in an effort to better understand how genomes work, and potentially allow some ‘control’ at genome level. As part of the synthetic yeast genome project, or Sc2.0, the researchers have introduced a synthetic right arm of the ninth chromosome, synIXR, and a partially synthetic left arm of the sixth, semisyn-VIL.

   

Figure 1: S. cerevisiae.

(Source: Wikimedia Commons, user: Masur)

   

Study You Don't Need To Read: Getting Drunk And Passing Out Makes You More Likely To Die In A Fire

Study You Don't Need To Read: Getting Drunk And Passing Out Makes You More Likely To Die In A Fire

Sep 15 2011 | comment(s)

A study in the Journal of Studies on Alcohol and Drugs says what you already knew - if you get drunk and pass out, you are more likely to die in a fire you could easily have escaped, if you weren't hammered drunk and sleeping on the floor.

Bonus: they manage to take shots at smokers too. 

The researchers' recommendation; have a designated house sitter.  Yes, if you are going to pass out drunk, have someone sober staying at the house. Because all sober people want to watch you get smashed.
How To Take Your Squid Home

How To Take Your Squid Home

Sep 15 2011 | comment(s)

I must have missed that section in the What to Expect books on how to react when your child comes home from school with a Ziploc bag filled with squid parts in his backpack.
Thus begins an entertaining account by Beth Braccio in the Chicago Parent about all the exciting things her son has brought home from school. To her credit, she didn't immediately make him throw the bag of squid away:
24 Hours of (Climate) Reality

24 Hours of (Climate) Reality

Sep 14 2011 | comment(s)

24 Presenters. 24 Time Zones. 13 Languages. 1 Message.

 24 Hours of Reality is a worldwide event that will share information about climate change. From Tonga to Cape Verde, Mexico City to Alaska, Jakarta to London, people will tell stories about what climate change means to them. The event features a new multimedia presentation created by Al Gore and delivered once per hour for 24 hours, in every time zone around the globe.

 The event starts at 8 PM USA Eastern Time.

More information:

English: http://climaterealityproject.org/the-event/
Chinese: http://forms.climaterealityproject.org/event-zh
Spanish: http://forms.climaterealityproject.org/event-es
Indonesian: http://forms.climaterealityproject.org/event-id
Propanoplosaurus Marylandicus: A Win For Open (And Citizen) Science

Propanoplosaurus Marylandicus: A Win For Open (And Citizen) Science

Sep 14 2011 | comment(s)

In 1997, Ray Stanford, a citizen scientist dinosaur tracker who often spent time looking for fossils close to his Maryland home, was searching a creek bed after an extensive flood and discovered a fossil which he identified as a nodosaur. 

Nodosaurs have been found in diverse locations worldwide, but they've rarely been found in the United States.  The area had originally been a flood plain, where the dinosaur originally drowned and it was tiny -  only 13 cm long, just shorter than the length of a dollar bill. Adult nodosaurs are estimated to have been 20 to 30 feet long.
Farewell To The Climber

Farewell To The Climber

Sep 14 2011 | comment(s)

Walter Bonatti died yesterday at 81 years of age. One of Italy's greatest "old style" climbers, Bonatti is especially famous for the first ascent to the K2, the extremely hard to climb, 8611-meter-tall mountain in the Karakorum.
When Common Sense Fails: Checklists To Save You From Woo

When Common Sense Fails: Checklists To Save You From Woo

Sep 14 2011 | comment(s)

Sometimes, when things are bad enough, we'll cave in and buy into concepts and products that we otherwise wouldn't have. As one example, hurt bad enough and you'll try just about anything to ease that pain. And unfortunately, common sense isn't nearly as common as it should be and we are none of us as skeptical as we could be. Except for those Missourians, of course, who live by the motto, "Show me." I'm honestly not too sure of that, though, as "showing" people works all too well or those power bracelets and other pseudoscience-based products wouldn't be so popular.
Math Links and Creepy Art

Math Links and Creepy Art

Sep 13 2011 | comment(s)

Squid news has been kind of slow lately, but I hate leaving this blog empty! (The frequency with which it is meant to be updated is, after all, given away in the title.)

So here are a couple of tidbits. First, a creepy illustration by Kevin Evans:


BioRap: Artificial Blood Cells From A Printer

BioRap: Artificial Blood Cells From A Printer

Sep 13 2011 | comment(s)

A 3-D inkjet printer can generate 3-dimensional solids from a wide variety of materials very quickly by applying the material in layers of defined shape and then bonding these layers are with UV radiation.  It can create microstructures but 3-D printing technology is still too imprecise for the fine structures of capillary vessels.

Perhaps not for long.

Researchers at Fraunhofer are applying new techniques and materials to come up with artificial blood vessels in their BioRap project. In the future that may mean artificial tissue and maybe even complex organs in future. 
Plummeting Satellites

Plummeting Satellites

Sep 13 2011 | comment(s)

I've talked about how our Project Calliope picosatellite will burn up entirely upon reentry.  Larger stuff, not so easy.  UT reports in the cutely titled "Look Out Below!" that the 6-ton URAS is going to reenter, messily, this Fall.
Shaking Some Preconceptions In Statistics

Shaking Some Preconceptions In Statistics

Sep 13 2011 | comment(s)

I enjoyed a lot reading a "discussion" prepared by Maury Goodman on the value of "confidence level", discovery thresholds, and what physicists believe or not. If you are a HEP physicist and you want to widen your horizons on the value of statistical claims in experimental results, you are bound to read it. But you might find it thought-provoking and enlightening even if you are a layman, provided you can use three neurons in a row.

A few random excerpts should convince you to read the whole piece:

Manjib:  No reasonable high energy physics will believe a two sigma effect.

Lifelong Musicians Experience Fewer Age-Related Hearing Problems Than Non-Musicians

Lifelong Musicians Experience Fewer Age-Related Hearing Problems Than Non-Musicians

Sep 13 2011 | comment(s)

Does playing music lead to less age-related hearing problems or do people without hearing problems continue to play music?

Hearing studies have shown that trained musicians have highly developed auditory abilities compared to non-musicians but a new study concludes hearing abilities in musicians and non-musicians differs, across the age spectrum from 18 to 91 years of age, and that musicians retain a keener ability to  detect and discriminate acoustic information from the environment.
Can Cheerleaders Successfully Market Science?

Can Cheerleaders Successfully Market Science?

Sep 13 2011 | comment(s)

www.sciencecheerleader.com, an organization started by the dynamic and committed citizen scientist Darlene Cavalier, has a noble goal. It wants to demonstrate to young girls that it’s OK to be pretty, smart, and love science. In fact, all of the cheerleaders want young girls to believe in themselves and do what they love to do.

At the first USA Science&Engineering Festival in 2010, the Science Cheerleaders drew large crowds, as they shook their pompoms, did a brief summary of what kind of scientists and medical specialists they are, and joined in unison to yell “Go Science.”