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Melville on Science vs. Creation Myth

From Melville's under-appreciated Mardi: On a quest for his missing love Yillah, an AWOL sailor...

Non-coding DNA Function... Surprising?

The existence of functional, non-protein-coding DNA is all too frequently portrayed as a great...

Yep, This Should Get You Fired

An Ohio 8th-grade creationist science teacher with a habit of branding crosses on his students'...

No, There Are No Alien Bar Codes In Our Genomes

Even for a physicist, this is bad: Larry Moran, in preparation for the appropriate dose of ridicule...

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Michael WhiteRSS Feed of this column.

Welcome to Adaptive Complexity, where I write about genomics, systems biology, evolution, and the connection between science and literature, government, and society.

I'm a biochemist

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I missed this interesting discussion at Larry Moran's Sandwalk: Are biochemistry programs too hard compared to other biology majors? Larry says his biochemistry program is losing students to other biology majors that don't require as much physics and chemistry - hard subjects by any standard. Is this a problem? If you want a career in biology, I think the answer is yes.
Science writer Carl Zimmer is building anticipation for his new book, Microcosm: E. coli and The New Science of Life. His latest hype-building piece is up at Wired. It's short and worth checking out.
Ethical debates over cloning are confusing enough, but even without the ethics issues the terminology of cloning is extremely confusing. Scientists bat around the word in many different contexts, often with subtly different meanings; if you don't know the biological background, it's easy to become disoriented. The most common use of the word cloning (in science, although maybe not in politics) has nothing to do with embryos, stem cells, or 10,000 copies of Jango Fett on the planet Kamino. It essentially means this (we'll call this definition 1): to make a copy of a piece of DNA, usually in order to put it into some form that's useful in the lab.
Interested in being a scientist? Then you had better get used to rejection and failure, because the truth is that most of your experiments will fail, most of your original ideas will be wrong, and most of your grant proposals and papers will be rejected on the first submission (especially if you submit to competitive journals). This doesn't mean you're a bad scientist - failure and rejection is a normal fact of life for most scientists (that is, all scientists except ones who aren't doing any science!). But this means that peer-review is a good thing, even when it affects you personally as your paper gets rejected (as mine was last week). How does peer review work in scientific publishing?

We go back a long way with herpesviruses. Our evolutionary line has been living with these genomic parasites for more than 100 million years, and today herpesviruses infect nearly all humans, as well as all other mammals, birds and reptiles that scientists have checked. We aren't born with these viruses, but most of us acquire multiple infections of various types of herpesviruses during childhood.

Unlike our relationship with many other, more notorious viruses, we've learned to peacefully coexist with herpesviruses for the most part. They set up shop in our cells, they use our molecular machinery to replicate themselves, and they take advantage of the influx of energy we provide from our diet. Sometimes the relationship goes sour, with the unfortunate results ranging from chickenpox to mononucleosis, genital herpes, and Burkitt's lymphoma, but by and large, most humans, and mammals in general, are never seriously harmed by these house guests. But do we get anything out of this relationship? Remarkably, recent research suggests that this 100 million-year coexistence may have been good for us too, helping our immune system to ward off even more serious pathogens.


Photo Credit: US Centers for Disease Control, courtesy of the Wikipedia Commons

There is no better way to fall into an IRS black hole than to try to become a scientist.

I'm a postdoctoral fellow - which means that I have my PhD, but no permanent job; I'm spending a few years doing research in a lab run by a more senior scientist. This is a typical part of the career path for most people in the natural sciences who want to direct their own labs at a research university or with a company.