Aging

While the average lifespan of those who reach adulthood has continued to rise those years spent living without health issues have not kept pace.

From 1970 to 2005, the probability of a 65-year-old surviving to age 85 doubled, from about a 20 percent chance to a 40 percent chance and the presumption was that the same changes allowing people to live longer, including medical advances, would delay the onset of disease and allow people to spend fewer years of their lives with debilitating illness.

Instead, a 20-year-old today can expect to live one less healthy year over his or her life span than a 20-year-old a decade ago.

What gives?
As life expectancies increase, so does the number of elderly people undergoing surgical procedures.    Recently, there has been growing about potential neurotoxicity of anesthetics and their role in post-operative cognitive decline.

Alzheimer's Disease(AD) is a devastating disease most commonly found in elderly people. It is manifested by severe memory loss, language problems, impaired decision making and affected activities of daily living.
There are three key factors associated with what gerontologists call "successful aging" - avoiding disease, maintaining physical and cognitive function, and continuing social engagement in late life.  But why do some groups clearly have those factors more than others?

One of the most recognized markers of cellular aging is the progressive accumulation of damage in the DNA, a molecule that cannot tolerate the alteration of the genetic information coded in its bases.

New research suggests that walking at least six miles per week may protect brain size and in turn, preserve memory in old age. 

For the study, 299 dementia-free people recorded the number of blocks they walked in one week. Then nine years later, scientists took brain scans of the participants to measure their brain size. After four more years, the participants were tested to see if they had developed cognitive impairment or dementia.
A new study published in Cell Metabolism says it has increased the lifespan of middle-aged mice by 12% using a combination of three amino acids as supplements.

Branched-chain amino acids (BCAAs) have extended life span in yeast but this is the first time these amino acids have been shown to work in mammals, the researchers say. 
A major blow to the free radical theory of aging, which has lead the research in aging for more than 50 years and fuels a multimillionaire anti-aging industry has just been published by Portuguese scientists from the University of Minho.

According to the theory, free radicals provoke oxidative damage and this is the cause of aging. The new work, however, shows that not only is possible to slow down aging in cells with high levels of oxidation but more, that a free radical (H2O2) is behind the high longevity seen with low caloric diets (a well known method to increase lifespan) turning upside down the way we see anti-aging therapy and research with major implications for the field.

There are some Happy Coffins from Singapore challenging death's taboos. Today, designer coffins deck a nursing home where three residents fulfill their pre-departure wishes about how their final resting places should look. 


"Without any fear," Elsie Chua said, "I am not afraid to talk about my eventual departure. It is very meaningful to be able to shape the design of my coffin and see it before I die.   I want to have a matching kebaya to go along."


 A kebaya is a traditional Straits Chinese garment for women. 


The art of dying


Elsie's wish was granted through an initiative between the Lien Foundation, a Singapore philanthropic house and St Joseph's Home and Hospice.


A scam is in the making!  Today I received this email:
Dear Colleague,
I’m writing to you about an extraordinary endeavor, the iHumans Project, which is outlined at: http://www.ihumansproject.org.
I hope you find the iHumans Project inspiring and you will be willing to share your thoughts and suggestions. Thank you!
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cbandea@ihumansproject.org
iHumans Project
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Based on the website domain's whois info, the full contact info is:
Admin Name:Claudiu Bandea
A reality check on“healthy aging.”  The real troubles - and opportunities - of a gero-nation go unheeded.

The numbers are increasingly disturbing: By 2050, some 88 million Americans will be over 65, with more than 20 million over 85. That such huge demographic shifts portend a challenge to the medical system goes without saying. 

The traditional American response holds that such needs will be filled by an innovative business culture responsive to market demand.