Aging

Gerovital H3, one of the "fountain of youth" miracles drugs that crop up once a generation, was banned in the United States in 1982, but the alternative medicine crowd that never let go of homeopathy after hundreds of years is reviving it. Anti-aging and longevity clinics now promote Gerovital H3 in pill form and as intravenous infusions.

Gerovital H3 is the dental anesthetic procaine hydrochloride (novocaine) but in the 1950s it was abused, unsurprisingly, by the Hollywood elites who gravitate toward fad diets and miracle treatments.

We constantly grow new skin and shed the old but no one is sure exactly how it works. New research says they may provide the answer. 

Engineers and biologists at the University of Sheffield say a recent hypothesis - that skin has 'sleeping' stem cells which can be woken up when required - best explains how our skin constantly regrows. The research, conducted by The Procter&Gamble Company (P&G), makers of Olay, and the University of Sheffield and published in Nature Scientific Reports, may have implications for combating the effects of aging.


Interacting with a therapeutic robot companion made people with mid- to late-stage dementia less anxious and also had a positive influence on their quality of life, according to a pilot study

PARO, a robotic harp seal, was used to investigate the effect of interacting with an artificial companion compared with participation in a reading group. PARO is fitted with artificial intelligence software and tactile sensors that allow it to respond to touch and sound. It can show emotions such as surprise, happiness and anger, can learn its own name and learns to respond to words that its owner uses frequently.
Scientists have a new theory as to why a woman’s fertility declines after her mid-30s: As women age, their egg cells become riddled with DNA damage and die off because their DNA repair systems wear out. Defects in one of the DNA repair genes, BRCA1, have long been linked with breast cancer and now also appear to cause early menopause.

Combining Medicare's hospital, physician, and prescription drug coverage with private supplemental coverage into one health plan could save the government and seniors $180 billion over a decade, according to a new analysis from The Johns Hopkins Bloomberg School of Public Health and advocacy group The Commonwealth Fund. 

Under the proposed plan, called "Medicare Essential," Medicare costs would be $63 billion lower between 2014 and 2023, with total premium and out-of-pocket costs for beneficiaries estimated to be 17 percent to 40 percent lower than current costs.


You've seen it on television; a rich, older man who supports a younger, attractive spouse. And it happens in real life, but it's rare.

Instead, a new analysis by economists has found that people married to much younger or much older mates have lower average earnings, lower cognitive abilities, are less educated and even less attractive than couples of similar ages.


Researchers have taken a step forward in efforts to help people with memory loss tied to brain disorders, such as Alzheimer's disease. Using sea snail nerve cells, the scientists reversed memory loss by determining when the cells were primed for learning. The scientists were able to help the cells compensate for memory loss by retraining them through the use of optimized training schedules. 

This latest study builds on a 2012 investigation that pioneered this memory enhancement strategy. The 2012 study showed a significant increase in long-term memory in healthy sea snails called Aplysia californica, an animal that has a simple nervous system, but with cells having properties similar to other more advanced species including humans.


Amyloids
are the quintessential bad boys of neurobiology.
These clumps of misfolded proteins found in the brains of people with Alzheimer's disease and other neurodegenerative disorders muck up the seamless workings of the neurons responsible for memory and movement, and researchers around the world have devoted themselves to devising ways of blocking their production or accumulation in humans.

Understanding how amyloids form requires an understanding of the biology of proteins, which are essentially strings of smaller components called amino acids attached end to end. Once they're made, these protein strings twist and fold into specific three-dimensional shapes that fit together like keys and locks to do the work of the cell.


Alzheimer's research is always big news. The reason is simple: people are living longer and they also want to be living better. While progress in general health issues for seniors marches on, the brain remains trickier stuff. Instead of less Alzheimer's than in the past, we have more, thanks to better diagnosis and greater longevity. Once you reach a certain age, you are almost certain to have someone in your family with it. 

Regional spending is not linked to differences in survival of patients with advanced cancer, according to an analysis of Surveillance, Epidemiology and End Results (SEER)-Medicare linked data in the Journal of the National Cancer Institute.

Cancer care accounts for approximately 10% of Medicare spending, and costs are highest for cancer patients with late-stage disease. There are large regional differences in spending within the Medicare program - more seniors, more spending on Medicare, for example - however it is unknown if higher average regional spending for advanced cancer is linked to improved survival for individual patients with cancer.