We know that lifespan can be extended in some animals by restricting calories such as sugar intake shortly after birth.   Université de Montréal scientists now say that it's not sugar itself that is important in this process but the ability of cells to sense its presence.

Aging is a complex phenomenon and the mechanisms underlying aging are yet to be explained. What researchers do know is that there is a clear relationship between aging and calorie intake. For example, mice fed with half the calories they usually eat can live 40 percent longer. How does this work? 

A new hypothesis, published in today's Nature, suggests that Alzheimer's may be caused by a normal prenatal developmental process gone awry in the adult brain.

Before you cast aside years of beta-amyloid research or proclaim a cure is imminent, relax - the results are only from lab and mouse studies. The research indicates that beta-amyloid precursor protein "and DR6 are components of a neuronal self-destruction pathway, and suggests that an extracellular fragment of APP, acting via DR6 and caspase 6, contributes to Alzheimer's disease."

- Bioidentical Hormones for Physical Rejuvenation and Fitness

"The Curious Case of Benjamin Button" has come to the movie theatres around the globe. Benjamin Button is born with the appearance and physical maladies of an elderly man but continuously growing younger - ailments and visible signs of aging disappear.

While in the film the effect of rejuvenation was achieved by changing actors, make up, and digital processing, modern medical technology can provide gentle rejuvenation of the body by up to 15 years.

DDr. Karl-Georg Heinrich, Vienna-based expert in anti-ageing and cosmetic surgery: "Age-related hormone deficiency is one of the main reasons for premature ageing and can be treated by use of bioidentical hormones." His surgery Clinic DDr.

A study from the Harokopio University of Athens (Greece) says that adherence to a dietary pattern close to the Mediterranean diet, with high consumption of fish and olive oil and low red meat intake, has a significant impact in women skeletal health.

Results suggest that this eating pattern could have bone-preserving properties throughout adult life.

Diet is one of the modifiable factors for the development and maintenance of bone mass. The nutrients of most obvious relevance to bone health are calcium and phosphorus because they compose roughly 80% to 90% of the mineral content of bone; protein, other minerals and vitamins are also essential in bone preservation.
Participating in certain mental activities, like reading magazines or crafting in middle age or later in life, may delay or prevent memory loss, according to a study released today.

The study involved 197 people between the ages of 70 and 89 with mild cognitive impairment, or diagnosed memory loss, and 1,124 people that age with no memory problems. Both groups answered questions about their daily activities within the past year and in middle age, when they were between 50 to 65 years old. 
Hollywood stars of a certain age take note: Research at Berkeley Lab suggests that a protein linked to the spread of several major human cancers may also hold great potential for the elimination of wrinkles and the rejuvenation of the skin. If this promise bears fruit, the protein, called RHAMM, could one day replace injections with neurotoxins that carry such unpleasant side-effects as muscle paralysis and loss of facial expressions.
Gardening can offer enough moderate physical activity to keep older adults in shape but Kansas State researchers writing in the journal HortScience say that among the other health benefits of gardening is keeping older hands strong and nimble.

"One of the things we found is that older adults who are gardeners have better hand strength and pinch force, which is a big concern as you age," said Candice Shoemaker, K-State professor of horticulture.
A recent theory of aging says that caloric restriction may do the trick but the research is inconsistent; the mice in the most promising studies were weaned that way, something unlikely to happen in human children.    New research says even those studies may not be entirely accurate and that for lean mice – and therefore lean humans, if prior mouse studies were to be taken at face value  – caloric restrictions as an anti-aging strategy may be a pointless, frustrating and even dangerous exercise.

But for fat mice, dieting makes sense and will extend life, the researchers say.   That goes for people as well.
Women appear to suffer more from rheumatoid arthritis (RA) than men, according to research published in Arthritis Research and Therapy.

John Hawks reviews an article by Roni Caryn Rabin on the connection with glucose metabolism and age related cognitive decline.

The original authors made clear that we remember:

Previous observational studies have shown that physical activity reduces the risk of cognitive decline, and studies have also found that diabetes increases the risk of dementia. Earlier studies had also found a link between Type 2 diabetes and dysfunction in the dentate gyrus.