Aging

Some animals live longer when raised on low-calorie diets but now researchers at Washington University School of Medicine in St. Louis say that they can extend the life spans of roundworms even when the worms are well fed — it just takes a chemical that blocks their sense of smell.

Three years ago, the researchers, led by Kerry Kornfeld, M.D., Ph.D., reported they found that a class of anticonvulsant medications made the roundworm Caenorhabditis elegans live longer. But until now, they didn't quite know what the drugs did to give the worms their longevity.
Many people believe that as soon as you start using a skin cream, you have to continue with it; if you stop lubricating, your skin becomes drier than when you started. And now there is research to confirm for the first time that normal skin can become drier from creams. Izabela Buraczewska presents these findings in the dissertation she is publicly defending at Uppsala University in Sweden on October 24.
Researchers in Germany are describing a potential alternative to Botox and cosmetic surgery for easing facial wrinkles. Their study, scheduled for the November 5 issue of ACS' Crystal Growth&Design,  reports that high intensity visible light from light emitting diodes (LEDs) applied daily for several weeks resulted in "rejuvenated skin, reduced wrinkle levels, juvenile complexion and lasting resilience."

LEDs, if you're not a regular reader here (though you should be) are the miniature lights used in an array of products, from TV remote controls to traffic lights.
Over the past 30 years, the U.S. population has reduced its fat intake and increased its consumption of carbohydrates. During the same time period, obesity has been rising along with the prevalence of metabolic liver disease in which fatty deposits in the liver can lead to inflammation, fibrosis and cirrhosis. Some studies have suggested that a high carbohydrate diet leads to fat formation in the liver, although confirming the association has been difficult.

When carbohydrates are restricted, the liver relies more on substances like lactate and amino acids to form glucose, instead of glycerol. These findings are in the November issue of Hepatology.
In middle age we begin to lose myelin, the fatty sheath of "insulation" that coats our nerve axons and allows for fast signaling bursts in our brains. So if you want to be the best at anything requiring speedy brain reaction times, you'd better get it in by age 39.

Writing in Neurobiology of Aging, Dr. George Bartzokis, professor of psychiatry at the UCLA Semel Institute for Neuroscience and Human Behavior at UCLA, and colleagues compared how quickly a group of males ranging in age from 23 to 80 could perform a motor task and then correlated their performances to their brains' myelin integrity.

The researchers found a striking correlation between the speed of the task and the integrity of myelination over the range of ages. Put another way, after middle age, we start to lose the battle to repair the myelin in our brain, and our motor and cognitive functions begin a long, slow downhill slide.


Nestlé, the world's largest food and beverage company, has introduced Glowelle, a dietary supplement that they say protects and hydrates the inner and outer layers of the skin. Their marketing blurb says it is formulated with a proprietary(naturally) blend of high antioxidant vitamins (like vitamin A, vitamin C and vitamin E), phtyo-nutrients, botanical and fruit extracts and that drinking it will help fight the signs of aging.Glowelle's antioxidants help defend against the damage caused by free radicals, which are caused by pollution ... and the sun.


You know, the sun. Source of all life on Earth. It's apparently bad for you. Except for that vitamin C antioxidant they put in Glowelle, which you can get for free ... from the sun.

Death is one of the few fundamental inevitabilities of human existence. This event is both fear-invoking and inspiring. This understanding, it seems, shares a shadowy symbiotic relationship with our daily lives. The inevitable outcome of death generates the concept of a limited "time horizon" and creates value in passing time. Each of us, individually, marches toward the dusk of our "time horizon".

Francis S. Collins, M.D., Ph.D., a physician-geneticist and leader of the Human Genome Project, has been awarded with the new Inamori Ethics Prize from the Inamori International Center for Ethics and Excellence at Case Western Reserve University.


Variation in the gene for one of the receptors for the hormone vasopressin appears to be associated with how human males bond with their partners, according to an international team of researchers.

The researchers found that the "334" allele of a common AVPR1A variation, the human version of avpr1a studied in voles, seemed to have negative effects on men's relationship with their spouses.

"Our findings are particularly interesting because they show that men who are in a relatively stable relationship of five years of more who have one or two copies of allele 334 appear to be less bonded to their partners than men with other forms of this gene," says Jenae Neiderhiser, professor of psychology, Penn State. "We also found that the female partners of men with one or two copies of allele 334 reported less affection, consensus and cohesion in the marriage, but interestingly, did not report lower levels of marital satisfaction than women whose male partners had no copies of allele 334."

Elderly patients who are prescribed a conventional, or first-generation, antipsychotic medication are at an increased risk of death from cardiovascular or respiratory diseases as compared to those who take an atypical, or second-generation, antipsychotic medication, according to a study funded by the Agency for Healthcare Research and Quality.

The new study, “Potential Causes of Higher Mortality in Elderly Users of Conventional and Atypical Antipsychotic Medications,” recently posted online in the Journal of the American Geriatrics Society, adds to growing evidence that conventional antipsychotics may not be safer than atypical anitpsychotics for the elderly. Researchers had previously identified that such second-generation medications may pose increased mortality; the new study compares specific causes of death among elderly patients newly started on conventional vs. atypical antipsychotics.