WASHINGTON, D.C., Dec. 29, 2015 -- Thermal properties of cells regulate their ability to store, transport or exchange heat with their environment. So gaining control of these properties is of great interest for optimizing cryopreservation -- the process of freezing and storing blood or tissues, which is also used when transporting organs for transplants.

Cell activity influences thermal properties, and at the tissue level this explains why infected wounds feel warm to the touch. Cancer cells, in particular, contain a thermal signature that reflects a higher metabolism than those of healthy cells. This feature is useful for grading tumors and can be used to complement classical histological analysis.

Euglena gracilis, the single cell algae which inhabits most garden ponds, has a whole host of new, unclassified genes which can make new forms of carbohydrates and natural products. Euglena creates many well-known, valuable natural products including vitamins, essential amino acids and a sugar polymer which may have anti-HIV effects. 

(PHILADELPHA) - Although the most common type of lung cancer - non-small cell lung cancer (NSCLC) - has recently seen major treatment advances in some genetic subtypes, other subtypes continue to evade effective treatment. (New therapies exist for NCCLC patients whose cancers harbor mutations in the ALK or EGFR genes, for example.) Now, a new study in mice has shown that cancers with KRAS-related gene mutations might benefit from a triple therapy with two experimental drugs plus radiation therapy. The results were published [TKTK date] in the journal Clinical Cancer Research.

The high amounts of dietary sugar in the typical Western diet may increase the risk of breast cancer and metastasis to the lungs, according to a study at The University of Texas MD Anderson Cancer Center.

The findings, published in the Jan. 1, 2016 online issue of Cancer Research, demonstrated dietary sugar's effect on an enzymatic signaling pathway known as 12-LOX (12-lipoxygenase).

"We found that sucrose intake in mice comparable to levels of Western diets led to increased tumor growth and metastasis, when compared to a non-sugar starch diet," said Peiying Yang, Ph.D., assistant professor of Palliative, Rehabilitation, and Integrative Medicine. "This was due, in part, to increased expression of 12-LOX and a related fatty acid called 12-HETE."

Diabetes is one of the leading causes of death. Patients with type 1 diabetes have their insulin secreting cells destroyed by the immune system and require daily insulin injections. Pancreatic islet transplantation is an effective treatment that can dramatically reduce daily doses or even eliminate dependence on external insulin. Insulin producing cells are injected into a recipient liver and after an adaptation period they start to produce sufficient hormone needed by diabetic patients.

Researchers have identified the requirements for the development of new types of extremely low power consumption electric devices by studying Cr-doped (Sb, Bi)2Te3 thin films. 

At extremely low temperatures, an electric current flows around the edge of the film without energy loss, and under no external magnetic field. This attractive phenomenon is due to the material's ferromagnetic properties but it has been unclear how the material gains this property until now.

The bacterium Bacillus cereus had so far been considered to be exclusively endospore-forming. In response to harsh conditions, the bacteria form protective endospores enabling them to remain dormant for extended periods, then they reactivate to become fully functioning bacteria when conditions are favorable again.
Nadine, a friendly human-like robot at Nanyang Technological University in Singapore will greet you back and shake your hand. Unlike conventional robots, the inventors say Nadine has her own personality, mood and emotions, and the next time you meet her, she will remember your name and your previous conversation with her.

She looks almost like a human being, with soft skin and flowing brunette hair. She smiles when greeting you, looks at you in the eye when talking, and can also shake hands with you. She can be happy or sad, depending on the conversation. Nadine is the doppelganger of its creator, Prof Nadia Thalmann, powered by intelligent software similar to Apple’s Siri or Microsoft’s Cortana. 
In the spirit of year end top 10 lists, but not restricting myself to 2015, I offer the following as the best 10 books ever written on the topic of obesity and/or weight loss.

1. Good Calories, Bad Calories, by Gary Taubes

Researchers say that the actions of individual farmers should be considered when studying and modelling strategies of pest control.

Research published in PLOS Computational Biology presents a model to understand the actions of humans and the dynamics of pest populations. The authors demonstrate this by using the example of the European corn borer, a moth whose larval phase is a major pest of maize.

Using game theory the researchers found that the farmers' perceptions of profit and loss, alongside communication networks between individuals, affects pest populations. A farmer's decision on whether to control a pest is usually based on the perceived threat of the pest and the guidance of commercial advisors.