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    Twins: Identical, Mirror Images, Fraternal And Chimeras
    By Sarda Sahney | October 23rd 2007 04:42 AM | 1 comment | Print | E-mail | Track Comments
    About Sarda

    Sarda Sahney is a Ph.D. student at the University of Bristol studying macroevolution, with focus on the evolution of vertebrate communities. View Sarda's Profile

    Cloning is not a human invention; nature has been creating clones for millions of years, among all organisms including humans. Nature’s clones, identical twins, are born in approximately 1 / 1000 births. Identical twins come in two varieties: identical and mirror images. Both share 100% of their DNA and but in mirror image twins, small differences are ‘reflected’. Examples include skin variations such moles, dental patterns, hairlines and handedness.

    The development of a truly identical twins versus mirror image twins comes down to timing. A single sperm will fertilize a single egg and begins development by splitting into more cells. If this group of cells, now called blastocyst splits into two separate parts in the first 9-12 days, identical twins will be born. But if the split occurs after that, they will be mirror-images of each other.

    Fraternal twins are an entirely different matter. Fraternal twins are no more identical than any other sibling pair and are the result of two separate sperm fertilizing two separate eggs. This is can occur naturally, the result of the mother releasing more than one egg at ovulation. It may also be the result of medical intervention as many women take fertility drugs to improve their chances of conception. There is also a hereditary link as the incidence of fraternal twins do occur more often within a family.

    Many people have seen the popular American television show CSI (Crime Scene Investigators) and may recall the episode with the Chimera, a man who had two sets of DNA. This phenomenon occurs when the blastocysts of developing fraternal twins fuse, resulting in a single individual with two sets of DNA. This condition usually results in a fully functional individual and is not detected unless a clear abnormality prompts testing. Though it has been considered a rare condition, it is found to be more common than originally thought in a variety of animals, including humans. And the condition is more common among children conceived through in vitro fertilization than naturally.

    By the way, you can read about the amazing birth of identical quadruplets from my hometown, Calgary, Canada here.

    Comments

    My 23 year niece was jut diagonsed with a gliobastoma brain tumor that surgical intervention is not an option. in the last two weeks the tumor has grown from walnut size to a banana shape and has 3 tails/runners that go toward the middle of the brain. my question is that she has a fraternal twin brother---what are his chances of having the same tumor or any brain tumor in the future? Their paternal great grandparents both died from bone/colon cancer. Would this also warrent having my seven year old screened as well?

    I would appreciate and insight or reply. Thank you for your time in advance.

    A very concerned Aunt & mother.

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