If you were pregnant, did you ever take a Tylenol?
If not, you have unreal levels of tolerance for discomfort but if you did, and you think your child is hyperactive, a new study may have some answers. Not 'why' answers, just a 'perhaps' answer. But look for mainstream media to declare that Tylenol causes attention-deficit/hyperactivity disorder (ADHD) in kids.
Acetaminophen is the most commonly used medication for pain and fever during pregnancy. But some studies have suggested that acetaminophen has effects on sex and other hormones, which can in turn affect neurodevelopment and cause behavioral dysfunction. The authors of a new paper in JAMA Pediatrics studied 64,322 children and mothers in the Danish National Birth Cohort (1996-2002). Parents reported behavioral problems on a questionnaire, and hyperkinetic disorders (HKDs, a severe form of ADHD) diagnoses and ADHD medication prescriptions were collected from Danish registries.
They found that more than half of the mothers reported using acetaminophen while pregnant. No surprise there. But then they also found that the use of acetaminophen during pregnancy appeared to be associated with a higher risk of HKD diagnosis, of using ADHD medications or of having ADHD-like behaviors at age 7 years. The risk increased when mothers used acetaminophen more than one trimester during pregnancy.
“Maternal acetaminophen use during pregnancy is associated with a higher risk for HKDs and ADHD-like behaviors in children. Because the exposure and outcomes are frequent, these results are of public health relevance but further investigations are needed,” they conclude.
In an accompanying editorial (JAMA Pediatr doi:10.1001/jamapediatrics.2013.5292), Miriam Cooper, M.R.C.Psych, M.Sc., of Cardiff University School of Medicine, and colleagues write, “Indeed, causation cannot be inferred from the present observed assocaitions, and Liew et al are right to point out that a replication of their study is needed.
“In summary, findings from this study should be interpreted cautiously and should not change practice. However, they underline the importance of not taking a drug’s safety during pregnancy for granted, and they provide a platform from which to conduct further related analyses exploring a potential relationship between acetaminophen use and altered neurodevelopment.”
Citation: JAMA Pediatr, February 24, 2014. doi:10.1001/jamapediatrics.2013.4914
- PHYSICAL SCIENCES
- EARTH SCIENCES
- LIFE SCIENCES
- SOCIAL SCIENCES
Subscribe to the newsletter
Stay in touch with the scientific world!
Know Science And Want To Write?
- Inheritable Bacterium Controls Aedes Mosquitoes' Ability To Transmit Zika
- What Lies Beneath West Antarctica?
- Exodus 2100: Due To Climate Change
- Unified Mathematical Field Theory Talk
- How To Make Women's Tennis More Competitive
- Study Suggests Bipolar Disorder Has Genetic Links To Autism
- Star With Different Internal Driving Force Than The Sun
- "Just adding another link. Spinning Brains..."
- "Okay, yes I hadn't thought about clear walled aquariums. That's a good example :). Maybe its easier..."
- " I tried to form a number system with Z6 and I got the same thing as with Z4 ! I too am unclear..."
- "Or maybe homosexuals are just more messed up than average to begin with. Nope, can't be. It's always..."
- "Perhaps it is time that large groups assign some type of weighting to authors to indicate their..."
- War On Fun Fail: After Tax, Soda Sales Rise in Mexico
- Bed Bugs May Have A Favorite Color
- NASA: Rising CO2 Will Help Food Crops
- NRDC Sues EPA Over Fracking – Has The Settlement Been Pre-Arranged?
- Vaccinate Pregnant Moms to Protect Babies from the Flu
- Pure Unstructured Structured Water – Because Some People Will Buy Anything
- Recipients of 2016 Gruber Cosmology Prize announced
- Elderly women more likely to be overprescribed prescription drugs: UBC study
- Crossref to accept preprints in change to long-standing policy
- Inheritable bacterium controls Aedes mosquitoes' ability to transmit Zika
- The Venus flytrap: From prey to predator