Anti-depressants are having a bad decade. They've been increasingly implicated in acts of violence - it used to be that if a person had been treated by multiple therapists, society had done its part, and now society wonders if over-medicating and creating too many psychological labels are the problem rather than the solution.
Now antidepressants are increasingly linked to obesity.
As detailed in JAMA Psychiatry, Sarah R. Blumenthal, B.S., Massachusetts General Hospital, Boston, and colleagues analyzed electronic health records from a large New England health care system to collect prescribing data and recorded weights for adult patients (age 18 to 65 years) prescribed one of 11 common antidepressants. The potential health consequences could be significant because more than 10 percent of Americans are prescribed an antidepressant at any given time, while obesity is associated with a host of medical conditions, including cardiovascular disease, type 2 diabetes and high blood pressure.
The authors identified 22,610 adults - 19,244 adults treated with an antidepressant for at least three months and 3,366 who received a nonpsychiatric intervention. Compared with the antidepressant citalopram, patients treated with bupropion, amitriptyline and nortriptyline had a decreased rate of weight gain.
“Taken together, our results clearly demonstrate significant differences between several individual antidepressant strategies in their propensity to contribute to weight gain. While the absolute magnitude of such differences is relatively modest, these differences may lead clinicians to prefer certain treatments according to patient preference or in individuals for whom weight gain is a particular concern,” they write.
Citation: JAMA Psychiatry, June 4, 2014. doi:10.1001/jamapsychiatry.2014.414
- PHYSICAL SCIENCES
- EARTH SCIENCES
- LIFE SCIENCES
- SOCIAL SCIENCES
Subscribe to the newsletter
Stay in touch with the scientific world!
Know Science And Want To Write?
- Neil Tyson On The Politics Of Science Denial
- Corals: Not So Passive, They Are Nature's Tiny Engineers
- Mutating Ebola Viruses Not As Scary As Evolving Ones
- Global 'Roadmap' Shows Where To Put Roads Without Costing The Earth
- Created: Renewable Propane Using E.coli
- How The Higgs Became The Target Of Run 2 At The Tevatron
- Low Carb Vs. Low Fat Diets: Which Is Better?
- "He used the term 'liberal' and thus so I did I, for the sake of consistency. In Science Left Behind..."
- "Clever one, Hank! In fact, I do have to exercise quite a lot of my limited self-control over..."
- "At least fruit flies have survived...."
- "Or put another way, a science blog should recognize the differences between: -Research that conclusively..."
- "Not to be rude - but the modern Left is Left - not liberal. I am Conservative, and would outscore..."
- An hour of moderate exercise a day may decrease heart failure risk
- Breast cancer patients with bilateral mastectomy don't have better survival rates
- Comparison of named diet programs finds little difference in weight-loss outcomes
- Increase seen in use of double mastectomy
- Study finds change in type of procedure most commonly used for bariatric surgery