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    Blue Light Phototherapy Has Potent Bacteria-Killing Ability
    By News Staff | December 17th 2013 07:00 AM | 2 comments | Print | E-mail | Track Comments

    Irradiation using light in the blue spectra has proven to have powerful bacteria-killing ability in laboratory studies using human and animal tissues.  

    "Bacterial resistance to drugs poses a major healthcare problem," says Co-Editor-in-Chief Chukuka S. Enwemeka, PhD, Dean, College of Health Sciences, University of Wisconsin--Milwaukee, in the accompanying Editorial "Antimicrobial Blue Light: An Emerging Alternative to Antibiotics," citing the growing number of deadly outbreaks worldwide of methicillin-resistant Staphylococcus aureus (MRSA). The articles provide evidence that "blue light in the range of 405-470 nm wavelength is bactericidal and has the potential to help stem the ongoing pandemic of MRSA and other bacterial infections."

    In the article "Effects of Photodynamic Therapy on Gram-Positive and Gram-Negative Bacterial Biofilms by Bioluminescence Imaging and Scanning Electron Microscopic Analysis," Aguinaldo S. Garcez, PhD and coauthors show that photodynamic therapy and methylene blue delivered directly into the root canal of a human tooth infected with a bacterial biofilm was able to destroy both Gram-positive and Gram-negative bacteria, disrupt the biofilms, and reduce the number of bacteria adhering to the tooth. 

    Raymond J. Lanzafame, MD, MBA, and colleagues demonstrated significantly greater bacterial reduction in the treatment of pressure ulcers in mice using a combination of photoactivated collagen-embedded compounds plus 455 nm diode laser irradiation compared to irradiation alone or no treatment. The antibacterial effect of the combined therapy increased with successive treatments, report the authors in the article "Preliminary Assessment of Photoactivated Antimicrobial Collagen on Bioburden in a Murine Pressure Ulcer Model."

    In "Wavelength and Bacterial Density Influence the Bactericidal Effect of Blue Light on Methicillin-Resistant Staphylococcus aureus (MRSA)," Violet Bumah, PhD and coauthors compared the bacteria-killing power of 405 nm versus 470 nm light on colonies of resistant Staph aureus and how the density of the bacterial colonies could limit light penetration and the bactericidal effects of treatment.




    Comments

    Straight from the pages of Wonder Woman, except... ok, theirs was a Purple Healing Light. And we have the old Violet Ray devices - which look to me like they put out significant UV in one range or another, which might have something to do with their healing properties if they killed off virii and bacteria...

    I've sometimes wondered if more complex waveforms than a simple sine wave, generated in the radio frequencies, might be able to create resonances that destructively reinforce and tear apart targeted segments of DNA unique to the organism being treated for. Of course, I'm no EM physicist or molecular biologist, so it's almost certainly just something I could use as handwavium in a SciFi story.

    Hank
    Everything has a resonant frequency. It's just when you get into higher frequencies that you have trouble getting any range. But for medical, since it could be contact-based, it would make sense.