It’s possible to assess dietary compliance from a blood sample - that is useful in controlled dietary intervention studies investigating the health benefits of specific diets, since such studies have mainly relied on the participants’ self-reported dietary intake, which is often biased, making it more difficult to assess the real health benefits.
In the recently published paper using results from the Nordic SYSDIET study, Dr. Matti Marklund and colleagues were able to identify the study participants with the greatest apparent compliance to a healthy Nordic diet by testing for a set of diet-related biomarkers in the blood. The beneficial effects of the diet on cardiometabolic risk factors, such as elevated blood pressure and blood lipids, were also greatest in this group. In all, there were 154 participants in the study.
Dietary biomarkers are compounds related to a certain food or nutrient that are measurable in bodily tissues and fluids, such as blood. In the SYSDIET study , the intervention group was advised to follow a healthy Nordic diet rich in berries, vegetables, fatty fish, canola oil, and whole grains. Several blood biomarkers were assessed to reflect the consumption of different key components of the diet, such as serum alpha linoleic acid as a biomarker of canola oil consumption, EPA and DHA reflecting fatty fish consumption, plasma beta carotene as a biomarker for vegetable intake and plasma alkylresorcinols reflecting whole grain consumption. High-fat dairy intake, which should be low in the healthy Nordic diet, was reflected by serum pentadecanoic acid.
The researchers conclude that when investigating the health effects of whole diets, it’s useful to measure multiple biomarkers reflecting the intake of different components of the diet. This way of assessing compliance also helps to better detect changes in risk factors.
In future studies, the combined use of biomarkers and participants’ dietary self-reports can improve dietary intake estimation and help to better evaluate the impact of the diet. In addition, informing participants that compliance will be assessed by dietary biomarkers might further motivate them to adhere to study diets.
Citation: Marklund M, Magnusdottir OK, Rosqvist F, Cloetens L, Landberg R, Kolehmainen M, Brader L, Hermansen K, Poutanen KS, Herzig KH, Hukkanen J, Savolainen MJ, Dragsted LO, Schwab U, Paananen J, Uusitupa M, Akesson B, Thorsdottir I, Risérus U. A Dietary Biomarker Approach Captures Compliance and Cardiometabolic Effects of a Healthy Nordic Diet in Individuals with Metabolic Syndrome. The Journal of nutrition 07/2014; DOI: 10.3945/jn.114.193771.
- PHYSICAL SCIENCES
- EARTH SCIENCES
- LIFE SCIENCES
- SOCIAL SCIENCES
Subscribe to the newsletter
Stay in touch with the scientific world!
Know Science And Want To Write?
- A Dimuon Particle At 30 GeV In ALEPH ??
- President Obama, Why Humans On Mars Right Now Are Bad For Science
- Who Is Trying To Destroy The Internet?
- DDoS war: How zombie fridges bit the internet in the a$$ today.
- A Racist On The Jews: Let The Donald Trump!
- Journalists - Please Fact Check Your "Doomsday" News Stories -They Terrify Young Children And Vulnerable People
- Metaphors in Quantum Mechanics
- "/* Hallelujah, HEP is saved! */ Are we doing research for saving some branch of physics? The science..."
- "Right, actually praying for something not to happen just focuses your mind on it - it doesn't tend..."
- "It's nonsense. He gives no sources and no astronomical reasoning at all. He makes it a matter of..."
- "Ive got a baby mr walker that i love with all my heart and this just petrifies me i keep getting..."
- "Sorry mr walker his name is spelt kinaeth madison he seems a very very big beliver in nibiru but..."
- The Math of Hunting and Fishing: When to Work Together
- Placebo: Bubbles Of Nothing Are Still Not Something
- People Who Take Drugs May Be Likelier to Commit Suicide
- Improved 'Screen Time' Guidelines Could Make Parents & Kids Happier
- Dr. Jamie Wells Named One Of America's Top Pediatricians
- Why Did EPA Delay Its Glyphosate Safety Report?