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    Illness Similar To Polio Found In Cluster Of California Children
    By News Staff | February 23rd 2014 09:56 PM | Print | E-mail | Track Comments

    Polio is an incurable, crippling, contagious and possibly fatal viral disease. The United States last experienced a polio epidemic in the 1950s, before a vaccine was introduced. 

    Today, it has been eradicated from most of the planet, but a polio-like syndrome has been found in a cluster of children from California over a one-year period, according to a case report released today.


    This time, it isn't California's anti-vaccine culture that is the problem. All of the children had been previously vaccinated against poliovirus. 

    The authors of the case study noticed several of these cases at their medical centers and decided to look for similar cases in California. They reviewed all polio-like cases among children who had samples referred to California's Neurologic and Surveillance Testing program from August 2012 to July 2013. Cases were included in the analysis if the children had paralysis affecting one or more limbs with abnormal MRI scans of the spinal cord that explained the paralysis. They did not include children who met criteria for Guillain-BarrĂ© syndrome and botulism, which can cause similar symptoms. 

    The five children experienced paralysis of one or more arms or legs that came on suddenly and reached the height of its severity within two days of onset. Three of the children had a respiratory illness before the symptoms began.  

    "Although poliovirus has been eradicated from most of the globe, other viruses can also injure the spine, leading to a polio-like syndrome," said case report author Keith Van Haren, MD, of Stanford University. Van Haren also works with co-author Emanuelle Waubant, MD, of the University of California, San Francisco. "In the past decade, newly identified strains of enterovirus have been linked to polio-like outbreaks among children in Asia and Australia. These five new cases highlight the possibility of an emerging infectious polio-like syndrome in California."

    The children were treated but their symptoms did not improve and they still had poor limb function after six months. Two children tested positive for enterovirus-68, a rare virus previously associated with polio-like symptoms. No cause was identified in the remaining three children.

    "Our findings have important implications for disease surveillance, testing and treatment," said Van Haren. "We would like to stress that this syndrome appears to be very, very rare. Any time a parent sees symptoms of paralysis in a child, the child should be seen by a doctor right away."


    Full results will be presented at the American Academy of Neurology's 66th Annual Meeting in Philadelphia, April 26 to May 3, 2014.  Source: American Academy of Neurology