A new corticosteroid hormone in the sea lamprey, an eel-like fish and one of the earliest vertebrates dating back 500 million years, may shed light on the evolution of steroid hormones.
Principal investigator and lead author David Close of the University of British Columbia's Department of Zoology andcolleagues at Michigan State University identified a corticosteroid hormone called 11-deoxycortisol in the sea lamprey that plays dual roles in balancing ions and regulating stresses, similar to aldosterone and cortisol in humans.
Native to the Pacific Coast of North America and Asia, Pacific lampreys are an important ceremonial and subsistence food for Aboriginal peoples in the Columbia River basin. They are born in freshwater, swim out to the ocean as adults and return to freshwater to reproduce in similar habitats to Pacific salmon and trout. Adult lampreys can grow to approximately 75 cm long and use their sucker-like mouth to attach to other fish while in the ocean.
Mouth of the Pacific lamprey. Credit: Wydoski and Whitney, 1979
"The origin of the corticosteroid signaling pathway has remained controversial over the past several decades because the identity of the ancestral corticosteroid has been elusive," says Close. "This discovery will help us better assess environmental and other stress factors on lamprey species – and provide insight into how stress-regulating hormones evolved from the earliest of vertebrates."
The findings will published online in the Proceedings of National Academy of Sciences Early Edition.
- PHYSICAL SCIENCES
- EARTH SCIENCES
- LIFE SCIENCES
- SOCIAL SCIENCES
Subscribe to the newsletter
Stay in touch with the scientific world!
Know Science And Want To Write?
- Sweet Irony: The Environmental Impacts Of GMO Sugar Science Denial
- Evidence Of Link Between Childhood Cancer And Phototherapy For Jaundice Examined
- How Does Obesity Cause Disease In Organs Distant From Those Where Fat Accumulates?
- Sexual Harassment in Science What Have We Learned (OP ED)
- When It Comes To Replicating Psychology Studies, Good Luck
- Distinguished European Scientists Challenge Endocrine Pseudoscience
- Networking Lets Sharks Off The Hook
- "This is pure, unmitigated nonsense. ..."
- "No, I am not saying a lack of belief will result in research showing something does not work. There..."
- "I think the text is quite easy to comprehend considering the difficulty of the subject matter...."
- "If you find a food without chemicals, please let the world know. You will get the biggest Nobel..."
- "Hi Tommaso, I think that the explanation can be understood with a bit of effort. However I am pretty..."
- When it comes to replicating studies, context matters, an analysis of reproducibility pro
- Squids on the rise as oceans change
- Loss of Y chromosome in blood is associated with developing Alzheimer's disease
- New disease gene will lead to better screening for pediatric heart disease
- Enhanced arginine metabolism may counteract inflammation pathways in asthma