Few things say as much about our culture as the food we eat. A new book, Glazed America: A History of the Doughnut by Paul R. Mullins, Ph.D., an Indiana University-Purdue University Indianapolis anthropologist, explores the development of America's consumer culture through our relationship with the doughnut; beloved by all but a symbol of temptation and unhealthiness to some.

It's unknown when in in pre-history someone dropped flour into oil but it happened and the ancestor of the doughnut was born. Since then, every culture has fried flour and many add something sweet to the dough.

Mullins is certainly a fan of his subject. He enjoys his doughnuts at an Indianapolis mom and pop shop which has been serving up those fried delicacies for 55 years, though he is also an avid runner who logs approximately 45 miles per week, often past that doughnut shop.

In a major step in understanding how the nervous system and the immune system interact, scientists at The Feinstein Institute for Medical Research have identified a new anatomical path through which the brain and the spleen communicate.

The spleen, once thought to be an unnecessary bit of tissue, is now regarded as an organ where important information from the nervous reaches the immune system. Understanding this process could ultimately lead to treatments that target the spleen to send the right message when fighting human disease.

Nutrients from the Amazon River spread well beyond the continental shelf and drive carbon capture in the deep ocean, according to the authors of a multi-year study. The finding does not change estimates of the oceans' total carbon uptake, but it reveals the surprisingly large role of tropical oceans and major rivers.

The tropical North Atlantic had been considered a net emitter of carbon from the respiration of ocean life. A 2007 study estimated that ocean's contribution to the atmosphere at 30 million tons of carbon annually.

Geoscientists at the California Institute of Technology have come up with a new explanation for the formation of monsoons, proposing an overhaul of a theory about the cause of the seasonal pattern of heavy winds and rainfall that essentially had held firm for more than 300 years.

The traditional idea of monsoon formation was developed in 1686 by English astronomer and mathematician Edmond Halley, namesake of Halley's Comet. In Halley's model, monsoons are viewed as giant sea-breeze circulations, driven by the differences in heat capacities between land and ocean surfaces that, upon heating by sunlight, lead to temperature differences between warmer land and cooler ocean surfaces--for example, between the Indian subcontinent and the oceans surrounding it.

For generations, people have consumed cranberry juice, convinced of its power to ward off urinary tract infections, though the exact mechanism of its action has not been well understood. A new study by researchers at Worcester Polytechnic Institute (WPI) reveals that the juice changes the thermodynamic properties of bacteria in the urinary tract, creating an energy barrier that prevents the microorganisms from getting close enough to latch onto cells and initiate an infection.

The study, published in the journal Colloids and Surfaces: B, was conducted by Terri Camesano, associate professor of chemical engineering at WPI, and a team of graduate students, including PhD candidate Yatao Liu. They exposed two varieties of E. coli bacteria, one with hair-like projections known as fimbriae and one without, to different concentrations of cranberry juice. Fimbriae are present on a number of virulent bacteria, including those that cause urinary tract infections, and are believed to be used by bacteria to form strong bonds with cells.

The question of whether insulin-producing cells of the pancreas can regenerate is key to our understanding of diabetes, and to the further development of regenerative therapies against the disease. Dr Rosenberg from the McGill University Health Centre (MUHC) and McGill University together with Dr Bernard Massie from the Centre hospitalier de l'Université de Montréal (CHUM) have just concluded that they can. The results of their study have been published in the July issue of the journal Laboratory Investigation.

The researchers have shown in vitro that insulin-producing β-cells (beta cells) can return to a more primitive developmental state called stem-like cells. This process is known as "dedifferentiation" and highlights the plasticity of this cell type. This same result has also been validated for the three additional types of cells that – along with β-cells – make up the islets of Langerhans. Together, these islet cells produce insulin and other hormones in the pancreas.