In the United States, billions of dollars have been spent on marketing to convince people to go into science careers, despite the difficulty many PhDs will have finding jobs in academia. That, coupled with the fact that efforts are on to make funding more 'equal' and establish quotas for young researchers, minorities and female grant applicants means a finite funding pool could be even more limited. The best and brightest, regardless of demographics, could end up leaving to other countries where science is more of a meritocracy.
Despite that, the BrightFocus Foundation says more federal funding is the answer, rather than common sense funding for the best research. They cite as evidence their survey of over 170 biomedical scientists who got funding from them, which implied that more funding would cure diseases like Alzheimer's, macular degeneration, and glaucoma. Welcome to The War On Cancer circa 1971.
It's no surprise, really. Insiders advocate their own research or they wouldn't be in the field, so 94% agreeing that a lack of federal funding for brain and eye disease research is impeding scientific discoveries is no shock. I also have never met anyone in the corporate world who felt like they were overpaid or that their jobs were not vital to the company - even union janitors at General Motors make $50 an hour with salary and benefits and they want that to go up.
But why this modern fetish with federal funding? In the recent generation of academic researchers, scientists - historically overwhelmingly distrustful of government - now regard government as the ultimate credibility. Over 50% of science is now under government control, despite the fact that private sector basic research has led to most of the biomedical breakthroughs of the last century. Biomedical research is the only area the government has not taken over yet - academia moves too slow, companies say - but increased regulations have created a climate where few companies can survive to a stage III clinical trial because venture capitalists see government interference as a blockade that is only going to get worse. They also regard the lawsuits by lawyers for every new product once it is on the market as a financial pincer. Culturally, academics have declared open war on the entire field, alleging that many papers published by corporate research groups are unethical, without presenting an alternate solution for drug discovery.
91% agreed that a lack of research funding is driving scientists from the field - which is also a little myopic in its conclusion. Are that many neuroscientists waiting tables in restaurants? The problem is we have too many researchers and advocates want to add more and then fund them with taxpayer money. That isn't really achievable. What is achievable is that the best researchers can be federally funded. Science is a meritocracy, the best researchers win. The others simply get jobs in that icky corporate world. Post-doc incomes are low because there are already too many PhDs trying to stay in college.
96 percent said limited funding was the top barrier to entry for new scientists in the fields of brain and eye disease research. Again, nothing will solve this problem. Every special interest claims it does not have enough funding so 96% of brain researchers are in favor of, what, unlimited funding? Well, aren't we all? The fact is that there is no barrier to entry for people who really want to do it - we have a modern problem where both government and universities instead insist they are 'competing with the private sector for the best people'. Academia used to be an occupation for people who loved research and did not care about money. With the advent of unlimited student loans and Pres. George Bush and Republicans doubling funding for the NIH and substantially raising science funding across the board, salaries ballooned. But unlimited student loans are going to end and federal funding is not going to double again either. We can't do anything about the generation in academia that has 6-figure salaries and expect raises while they sit in foreign jails(1) but young researchers of the future are going to be doing research for love of research, just like their ancestors did.
Guy Eakin, Ph.D., vice president of Scientific Affairs for BrightFocus Foundation, said in his statement,"The total U.S. health care cost for Alzheimer's alone is $200 billion annually and is expected to soar to $1.1 trillion per year by 2050 if we don't have the scientific discoveries made possible by research funding. Yet budget cuts for research continue, and we're losing the talents of a generation of scientists."
Does that number sound real? Expected by who? How? It seems a lot like that number record companies use to complain about music piracy, or that 'jobs saved or gained' employment figured pulled out of thin air by the government in 2009. When you read something like "expected to soar to $1.1 trillion per year by 2050 if we don't have the scientific discoveries made possible by research funding", it is wise to reach for your wallet.
NOTE:
(1) And that six-figure salary he gets is 18th out of 28 - just in his one department. Just at his one school. Academia is very much no longer toiling away by poor scholars.




There is now a wealth of evidence that pathological progression of dementias typically precedes symptom presentation by decades. A person can lose up to 80% of the neurons in the substantia nigra before they present with symptoms of Parkinson's Disease. One reason Big Pharma is walking away from dementia research could be that by the time of symptom presentation too many vicious cycles of degeneration have been set in play and trying to reverse those involves physiological processes that if targeted will create so many other problems as to make the intervention useless. It is easy to forget that physiological processes are not walled off from each other, that the perturbation of one process often involves problems with other processes. That, at least at present, creates very serious and often insurmountable problems.
By way of comparison consider the words of David Baltimore, a leading biologist involved in cancer research:
That is not to say we should give up entirely but seeking dementia cures at this point in time is somewhat premature. In dementia research a more realistic goal is to identify the prodromal markers and seek therapies at that point in time, even in the 40-50 age ranges. We cannot cure AIDS but have achieved tremendous progress in limiting progression of the disease. Transhumanists believe all sorts of cures are possible but that's just wishful thinking. We're all gonna die, get over it.
Corporate driven research certainly has its problems, especially in relation to psychiatric conditions. Far too much bullshit there and not enough prosecutions for the dodgy research and pushing of drugs for off label purposes. However recent prosecutions with huge fines(GSK) should prove a big wake up call to the rest.
Australia does extremely well in biomedical research but with very limited funding. If you limit funding perhaps only the really determined, those driven by passion to solve the problem will enter the field and put their heart and soul into their work, rather than those driven by salaries and career maintenance. It is a common feature of creative endeavours, be it artistic or scientific, that the success comes with tremendous dedication and resolve, not necessarily a huge budget and a very high iq. Here's one eg. The Aussie doctor who is credited with the cochlear ear implant said he was driven to do this because his father was a chemist but very deaf and would embarrass his customers because they would have to yell at him about their medical conditions.The doctor was inspired by that experience and developed a truly wonderful biomedical breakthrough. We ignore the power of passion and fail to appreciate that is often just as important as budgets and salaries; if often not more important.
BTW Hank, in Australia our publicly funded research institutions have done tremendous work. High salaries and big budgets do not equal high motivation, no matter what CEOs might think. It can make a person too comfortable. Now please excuse me, I must prepare my argument for a pay rise. :)