A new paper finds that widely available retinal imaging techniques may help reveal more about brain disease and monitor treatment efficacy, including a currently untreatable form of childhood-onset dementia, Sanfilippo syndrome.
Sanfilippo syndrome is one of a group of about 70 inherited conditions which collectively affect 1 in 2800 children in Australia, and is more common than cystic fibrosis and better known diseases. Around the world 700,000 children and young people are living with childhood dementia. The researchers studied Sanfilippo syndrome in mouse models, discovering for the first time that advancement of retinal disease parallels that occurring in the brain.