A Phase IIa placebo-controlled clinical trial of TOPOFEN, a topical anti-migraine therapy for moderate and severe migraine sufferers, showed that the application of a well-known non-steroidal anti-inflammatory drug (NSAID) over the trigeminal nerve branches can be a safe and effective alternative treatment for patients suffering from acute migraine.

With almost the same number of soldiers as the Australian and New Zealand Army Corps (ANZAC) – 79,000 – and similar death rates – close to 10,000 – French participation in the Gallipoli campaign could not occupy a more different place in national memory.

What became a foundation myth in Australia as it also did in the Turkish Republic after 1923 was eventually forgotten in France.

Some of the reasons are obvious.

It's time to bust the myth that anyone, and that includes athletes, can outrun a bad diet, say experts in an editorial in the British Journal of Sports Medicine. Excess carbohydrates, not physical inactivity, are behind the surge in obesity.

Regular exercise is key to staving off serious disease, such as diabetes, heart disease, and dementia, write the authors, but our calorie-laden diets now generate more ill health than physical inactivity, alcohol, and smoking - combined. The evidence they cite suggests that up to 40% of those within a normal weight (BMI) range will nonetheless harbor harmful metabolic abnormalities typically associated with obesity.

A Boston College expert in educational measurement is taking a look at the controversial college and university rankings lists that are promoted by schools hoping to lure full-fare students from out of state and parents and students who want validation for their choices.

Loss of muscle volume is a common debilitating outcome of traumatic orthopedic injury, resulting in muscle weakness and loss of limb function.  The current best solution is muscle graft but a new therapeutic approach uses small pieces of autologous muscle which can be expanded in a collagen hydrogel and used to regenerate functional muscle at the sight of injury.

A study demonstrating the feasibility of using autologous minced tissue grafts for muscle regeneration shows it would be better for repairing large areas of muscle loss.  

Some studies find that the immune system, which protects our bodies from foreign invaders, plays a part in Alzheimer's disease, though the actual role of immunity in the disease is a mystery.

A new Duke University study in mice suggests that in Alzheimer's disease, certain immune cells that normally protect the brain begin to abnormally consume an important nutrient: arginine. Blocking this process with a small-molecule drug prevented the characteristic brain plaques and memory loss in a mouse model of the disease.

Many newborns are exposed in their earliest days to bisphenol A (BPA) and lots of other chemicals, the world is all chemical, but BPA has been the subject of more scrutiny than most because it is ubiquitous. Due to that, environmental advocacy studies have claimed there is probably risk to adults and newborns, while more neutral science says that it is detectable but not harmful.

If you have hepatitis B or C and feel like you are treated poorly by others due to it, you are not alone. As many as half of people infected with viral hepatitis say they have suffered discrimination and one-quarter admit that family members have avoided physical contact with them after finding out they had the infection. 

What makes triple negative breast cancer more lethal in African-American women than European-American ("White") women? A new study reveals specific genetic alterations that appears to impact their prognosis and ultimately survival rates.

Seismologists have discovered a massive magma reservoir beneath the Yellowstone supervolcano in Wyoming, US, that suggests its volcanic system could be more than 5.6 times larger than was previously thought.