The American public loves underdogs, the outlier or even outcast who defies convention and is proven right.
Dr. Claude Wischik may be just that. He believes that a protein called tau, which forms twisted fibers known as tangles inside the brain cells of Alzheimer's patients, is largely responsible for driving the disease.
His theory that goes against much of the scientific community, which has spent 20 years and billions of dollars of pharmaceutical investment on a different protein, beta amyloid, which forms sticky plaques in the brains of sufferers. But a string of experimental drugs designed to attack beta amyloid have failed recently in clinical trials, including two this summer from Eli Lilly &Co. and a partnership involving Pfizer Inc., Johnson&Johnson and Elan Corp.
Wischik sees this as tau's big moment.
An Outcast Among Peers Gains Traction on Alzheimer's Cure by Jeanne Whalen, Wall Street Journal
- PHYSICAL SCIENCES
- EARTH SCIENCES
- LIFE SCIENCES
- SOCIAL SCIENCES
Subscribe to the newsletter
Stay in touch with the scientific world!
Know Science And Want To Write?
- Poisons Chemists Hate, But You Just Ate
- Our Ethical Responsibilities To Baby Terraformed Worlds - Like Parents
- Single Top Production At The LHC
- Supersymmetry Is About To Be Discovered, Kane Says
- Dietary Restriction, Circadian Rhythm, And Long Life
- Anomaly! - A Different Particle Physics Book
- New Open-access Data On Paleofloods
- "The reason I needed to do an article is because so many of you are so scared by it. I wouldn't..."
- "You have nothing to worry about or scared about by way of mythical bullshit planets :). I don't..."
- "Well it's not going to happen, and it's just so sad that so many of you are getting worked up about..."
- "Where is this article, out of interest?I'm not too surprised, that there'd be some reaction. After..."
- "some people are saying nibiru wont hit earth its just going to cause mayhem on our planet apparently..."
- Earth's first ecosystems were more complex than previously thought, study finds
- Soil pulled from deep under Oregon's unglaciated Coast Range unveils frosty past climate
- Mystery of how snakes lost their legs solved by reptile fossil
- Seizure risk of anti-shivering agent meperidine greatly overstated
- Immune-disorder treatment in mice holds potential for multiple sclerosis patients