The American public loves underdogs, the outlier or even outcast who defies convention and is proven right.
Dr. Claude Wischik may be just that. He believes that a protein called tau, which forms twisted fibers known as tangles inside the brain cells of Alzheimer's patients, is largely responsible for driving the disease.
His theory that goes against much of the scientific community, which has spent 20 years and billions of dollars of pharmaceutical investment on a different protein, beta amyloid, which forms sticky plaques in the brains of sufferers. But a string of experimental drugs designed to attack beta amyloid have failed recently in clinical trials, including two this summer from Eli Lilly &Co. and a partnership involving Pfizer Inc., Johnson&Johnson and Elan Corp.
Wischik sees this as tau's big moment.
An Outcast Among Peers Gains Traction on Alzheimer's Cure by Jeanne Whalen, Wall Street Journal
- PHYSICAL SCIENCES
- EARTH SCIENCES
- LIFE SCIENCES
- SOCIAL SCIENCES
Subscribe to the newsletter
Stay in touch with the scientific world!
Know Science And Want To Write?
- A Statistics Session At A Particle Physics Conference ?
- Beekeepers Can Be Hazardous To Bees
- Crossref To Accept Preprints In Change To Long-standing Policy
- Young Bisexual Women More Susceptible To Depression
- Wildlife Loss In Tropical Forests Is Bad News For Everyone
- The Number Of My Publications Has Four Digits
- 'Super Males' Emerge From Male-dominated Populations, Study Finds
- " Right on, this is nothing new, however, see Sam Kinisons' take on world hunger, it's hilarious..."
- "Because IARC has been taken over by an activist for Environmental Defense Fund, who got a rule..."
- "It could also be worth mentioning the eBook version is available for a 7 day free trial on Amazon..."
- "And BTW, I'll look forward to reading the book anyway. Always good to stay current. Scott...."
- "Truly astonishing. Honestly. my background was originally astrophysics but morphed into other fields..."
- Scientists are first to discover sensory system that detects air humidity
- The cause of high Tc superconductivity at the interface between FeSe and SrTiO3
- Breastfeeding is good for yet another reason, researchers discover
- Genetic variants in patients with crohn's disease prevent 'good' gut bacteria from working
- A crack in the mystery of 'oobleck' -- friction thickens fluids