The American public loves underdogs, the outlier or even outcast who defies convention and is proven right.
Dr. Claude Wischik may be just that. He believes that a protein called tau, which forms twisted fibers known as tangles inside the brain cells of Alzheimer's patients, is largely responsible for driving the disease.
His theory that goes against much of the scientific community, which has spent 20 years and billions of dollars of pharmaceutical investment on a different protein, beta amyloid, which forms sticky plaques in the brains of sufferers. But a string of experimental drugs designed to attack beta amyloid have failed recently in clinical trials, including two this summer from Eli Lilly &Co. and a partnership involving Pfizer Inc., Johnson&Johnson and Elan Corp.
Wischik sees this as tau's big moment.
An Outcast Among Peers Gains Traction on Alzheimer's Cure by Jeanne Whalen, Wall Street Journal
- PHYSICAL SCIENCES
- EARTH SCIENCES
- LIFE SCIENCES
- SOCIAL SCIENCES
Subscribe to the newsletter
Stay in touch with the scientific world!
Know Science And Want To Write?
- Part I: Bee Deaths Mystery Solved? Neonicotinoids (Neonics) May Actually Help Bee Health
- Smoking, Drinking And Eating: It's Not About Your Freedom
- Big Data Engineering - Now With More Neuroscience
- Part II: Bee Deaths And CCD - Flawed Chensheng Lu Harvard Studies Endanger Bees
- Coffee Lowers Risk Of Alzheimer's Up To 20 Percent
- Diversity Fatigue: Why Businesses Struggle To Close The Gender Gap
- Like Collaboration And Intelligence In Humans? Thank War
- "many will say - oh g-o-d, not that again - does not change the fact that social engineering via..."
- "No intelligent person believes tobacco controls' santimonious twaddle anymore. This is the purvey..."
- "A note from THE SIN OF PROHIBITION by G.K.Chesterton:So if you wish to change corporate behaviour..."
- "How can diseases linked to smoking tobacco be on the rise when the smoking rate has been consistently..."
- "I was looking at The Winnower again this morning, which led me back here. I tried to comment on..."
- Behavioral interventions to prevent progression to diabetes equally effective in men and women
- Gender differences in adaptation to space flight
- Long-term complication rate low in nose job using patient's own rib cartilage
- Survival differences seen for advanced-stage laryngeal cancer
- Effect of once-daily, low-dose aspirin on heart attack deaths and other outcomes