Want to lower your risk of developing the most common form of skin cancer, basal cell carcinoma? Drink more coffee, says a new study.
Basal cell carcinoma is the form of skin cancer most commonly diagnosed in the United States. Even though it is slow-growing, it causes considerable morbidity and places a burden on health care systems.
The researchers generated their results by conducting a prospective analysis of data from the Nurses' Health Study, a large and long-running study to aid in the investigation of factors influencing women's health, and the Health Professionals Follow-up Study, an analogous study for men.
Of the 112,897 participants included in the analyses, 22,786 developed basal cell carcinoma during the more than 20 years of follow-up in the two studies. An inverse association was observed between all coffee consumption and risk of basal cell carcinoma. Similarly, an inverse association was seen between intake of caffeine from all dietary sources (coffee, tea, cola and chocolate) and risk of basal cell carcinoma. However, consumption of decaffeinated coffee was not associated with a decreased risk of basal cell carcinoma.
"Our data indicate that the more caffeinated coffee you consume, the lower your risk of developing basal cell carcinoma," said Jiali Han, Ph.D., associate professor at Brigham and Women's Hospital, Harvard Medical School in Boston and Harvard School of Public Health. "I would not recommend increasing your coffee intake based on these data alone. However, our results add basal cell carcinoma to a list of conditions for which risk is decreased with increasing coffee consumption. This list includes conditions with serious negative health consequences such as type 2 diabetes and Parkinson's disease."
In contrast to the findings for basal cell carcinoma, neither coffee consumption nor caffeine intake were inversely associated with the two other forms of skin cancer, squamous cell carcinoma and melanoma, the most deadly form of the disease.
"These results really suggest that it is the caffeine in coffee that is responsible for the decreased risk of basal cell carcinoma associated with increasing coffee consumption," said Han. "This would be consistent with published mouse data, which indicate caffeine can block skin tumor formation. However, more studies in different population cohorts and additional mechanistic studies will be needed before we can say this definitively."
Only 1,953 cases of squamous cell carcinoma and 741 cases of melanoma were recorded among the 112,897 participants included in Han's analyses.
"It is possible that these numbers are insufficient for any association with coffee consumption to be seen," said Han. "As the study participants are followed for a longer time, the number of cases of these conditions is likely to increase. We may be in a position in 10 years' time to better address this issue."
Published in Cancer Research.
- PHYSICAL SCIENCES
- EARTH SCIENCES
- LIFE SCIENCES
- SOCIAL SCIENCES
Subscribe to the newsletter
Stay in touch with the scientific world!
Know Science And Want To Write?
- Highlights From ICNFP 2015
- Most Idiotic Rejection Of Course From Philosopher Of Science Not Grasping Relativity
- Artificial Intelligence: It's Time To Talk About What Emotions We Want AI To Have
- Supertranslations And Eternal Ghosts: Black Holes No Closer To Being Understood
- Innate GMO Potato Deregulated By USDA
- Lettuces Now, What Next - Could Astronauts Get All Their Oxygen And Food From Algae Or Plants?
- Brain Size Matters When It Comes To Remembering
- "The wavelength of the exiting radiation from the iguana asymptotically becomes zero, so I can't..."
- "The other thing that is weirdly suspicious is the picture mocking Hilarry Putnam. Now, the brains..."
- "My question is, exactly what was in this paper? He complains about the paper being rejected and..."
- "I wouldn't take it too hard buddy. Suppose they did publish it- then what, 20 more people might..."
- "I had some problems with Dr. Vongehr's short essay. One of them is the broken English. Now I am..."
- “Shock Therapy” – Not a Cuckoo’s Nest, a Valid Depression Rx
- Innate: Simplot genetically engineered potato gets USDA nod for deregulation
- Sorry, AIDS Deniers, It’s Only a Headline
- Mission Not Yet Accomplished on Vaccines
- Cigarettes, Now With An Organic Health Halo
- Bee Wary of Tales of the ‘Beepocalypse’
- Study reveals human body has gone through four stages of evolution
- Estimate claims plastic in 99 percent of seabirds by 2050 - but accuracy of the baseline is unknown
- Pollution and weather influence heart attack outcomes?
- Fish oil diet versus gut microbes
- Naps linked to reduced blood pressure and fewer medications