Like it or not, your mouth is home to a thriving community of microbial life. More than 600 different species of bacteria reside in this "microbiome," yet everyone hosts a unique set of bugs, and this could have important implications for health and disease. In a new stud, scientists have performed the first global survey of salivary microbes, finding that the oral microbiome of your neighbor is just as different from yours as someone across the globe.

Researchers at The Scripps Research Institute in La Jolla, California have identified a common Achilles' heel in a wide range of seasonal and pandemic influenza A viruses.

The study found an infection-fighting protein, or human antibody, that neutralizes various influenza A virus subtypes by attaching to these viruses in the same place. This common attachment site provides a constant region of the flu virus for scientists to target in an effort to develop a so-called universal flu vaccine.

Such a vaccine would overcome the annual struggle to make the seasonal flu vaccine match next year's circulating flu strains and might help blunt emerging pandemic influenza viruses as well. 

A biochemical analysis of a rare Clovis-era stone tool cache recently unearthed in the city limits of Boulder, Colo., indicates some of the implements were used to butcher ice-age camels and horses that roamed North America until their extinction about 13,000 years ago, according to a University of Colorado at Boulder study.

The study is the first to identify protein residue from extinct camels on North American stone tools and only the second to identify horse protein residue on a Clovis-age tool, said CU-Boulder Anthropology Professor Douglas Bamforth, who led the study. The cache is one of only a handful of Clovis-age artifact caches that have been unearthed in North America, said Bamforth, who studies Paleoindian culture and tools. 

A deep new image of the magnificent Helix planetary nebula has been obtained using the Wide Field Imager at ESO's La Silla Observatory. The image shows a rich background of distant galaxies, usually not seen in other images of this object.

A team of Vanderbilt scientists have invented what is basically the world's smallest periscope and are using it to look at cells and other micro-organisms from several sides at once.

The researchers have officially dubbed these devices "mirrored pyramidal wells" and they consist of pyramidal-shaped cavities molded into silicon whose interior surfaces are coated with a reflective layer of gold or platinum. They are microscopic in dimension – about the width of a human hair – and can be made in a range of sizes to view different-sized objects. When a cell is placed in such a well and viewed with a regular optical microscope, the researcher can see several sides simultaneously.

We learn a lot from genes but it turns out we can learn even more - like where you lived or even who you spent time with.   It just requires knowing where and how to look.

Researchers from Stanford and Tel-Aviv University are using a technique called "reverse ecology" to examine metabolic networks and pull out proxies for reconstructing bacterial environments millions of years in the past. The work, published in the February issue of the Journal of Computational Biology, offers clues to the complex evolutionary interplay between organisms such as parasites and hosts.