HIV and AIDS are huge threats to human health. Each day in 2005 around 7,600 people died from HIV-related causes and a further 38.6 million people were living with the disease. Two million of these were living in the high-income countries of North America and Western and Central Europe. Estimates suggest that that year 4.1 million people contracted the virus.

Estimates also suggest that 70% of HIV-infected people stay sexually active, with a substantial proportion continuing to participate in unprotected sex. On top of this there is a rising prevalence of other sexually transmitted infections including chlamydia and gonorrhoea in many high-income countries around the world.

A new Cochrane Review finds that programs that aim to encourage sexual abstinence while also encouraging and teaching safer sex strategies for those who are sexually active can reduce short- and long-term HIV risk behavior among young people in high-income countries.

Abstinence-plus programs start from the premise that sexual abstinence is the best way to prevent infection, but recognizes that some people will continue to be sexually active and therefore also helps to enable safe and effective use of condoms. In addition to teaching condom skills, abstinence-plus programs commonly teach about safer sex negotiation, communication with partners, and transmission of HIV and other sexually transmitted infections.

Cochrane Researchers therefore looked for evidence that specifically identified the effectiveness of abstinence-plus programs in high-income countries.

They found 39 studies involving over 37,000 North American young people. In 23 studies there was a significant increase in protective behaviour. None of the studies reported any adverse effects; contrary to criticisms against abstinence-plus programs, participants did not become more sexually active after completing the interventions. Owing in part to limitations in measurement, the results were unable to show evidence that abstinence-plus programs affected self-reported rates of sexually transmitted infections, or self-reported pregnancy incidence.

“In a previous Cochrane Review we concluded that abstinence-only programs have no effect in high-income countries, which makes the finding that abstinence-plus programs can influence behavior even more striking,” says lead researcher Dr Don Operario who works at the Department of Social Policy and Social Work at the University of Oxford, UK. “This is an opportunity for the HIV prevention and public health communities to harness the potential benefits of comprehensive sexual health education such as abstinence-plus programmes.”

Article: Underhill K, Montgomery P, Operario D. Abstinence-plus programs for HIV infection prevention in high-income countries. Cochrane Database of Systematic Reviews 2008, Issue 1. Art. No.: CD007006. DOI: 10.1002/14651858.CD007006.