Pharmacology
Using living cells as more efficient tools for delivering medicines to diseased parts of the body has gotten a little closer.
In a new report, Dayang Wang and colleagues explain that the human body's efficiency in getting rid of foreign substances can also be an obstacle. Some foreign substances, such as viruses, are harmful and should obviously be removed, but the body also considers drugs and nanoparticles — meant to treat diseases and allow physicians to see cells and organs — to be foreign objects, and they are also quickly removed.
Does high-fructose corn syrup, a common ingredient in soft drinks and snacks and too many products to count, make you fatter than sugar? The Sugar Association, Inc., which represents sugar growers, certainly wants you to think so.
But, like cultural pundits who insist Ronald McDonald makes kids fat, there needs to be more than one study funded by an interested party to make the case. A review of studies analyzing research on High Fructose Corn Syrup (HFCS) and other sweeteners found there is no evidence of any significant variation in the way the human body metabolizes HFCS as opposed to standard table sugar, or any difference in impact on risk factors for chronic disease.
There are perennials in the plant kingdom, flowers that bloom each year, and in culture as well. Each year, for example, there will be a new go-to cliché in football. Many of us who have watched for a long time can even tell you what year a broadcast was made by which cliche was in use.
Quiz: If I say they play "smash mouth football", what year was I thinking?
Thrombolytic agents, commonly called "clot-busting" drugs, are frequently used in the treatment patients with blood clots in the lungs but a new study says clot-busting drug are no more effective than traditional blood thinners for the majority of the patients who get them. Thrombolytic agents also appear to increase the risk of death in patients with normal blood pressure.
Leukotriene receptor antagonists (LTRAs)are easier to use and just as effective as conventional treatment with inhalers, according to a new study led by the University of East Anglia (UEA).
Asthma is an increasing problem affecting around 300 million people worldwide and can significantly impact on a person's quality of life. It is a chronic condition characterized by inflammation of the airways causing wheezing, coughing, chest tightness and shortness of breath.
Acetaminophen overdose has become the leading cause of acute liver failure in the U.S. How is that possible, when ingredients are printed clearly on the labels, along with warnings?
Acetaminophen's is in more than 600 over-the-counter and prescription medicines and people take billions of doses of over-the-counter pain relievers every year, but many do not pay attention to the active ingredients they contain, such as acetaminophen, according to a new Northwestern Medicine study.
Too many older adults are taking "excessive" doses of drugs for thyroid problems and that has been linked to an increased risk of fractures, according to a new study. The study raises concern that treatment targets may need to be modified in the elderly.
ADVANCELL has initiated a phase IIb clinical study of the Company's ATH008, for the treatment of the palmar-plantar erythrodysesthesia syndrome, also known as hand-foot syndrome, a painful side-effect of certain chemotherapies such as capecitabine and fluoropyrimidines. No treatment currently exists for this condition. ADVANCELL expects to launch the product on the market by the end of 2015 or beginning of 2016.
Amira Pharmaceuticals, Inc. announced today that AM152, the company's lead LPA1 antagonist, has been granted an orphan drug designation by the U.S. Food and Drug Administration for the treatment of idiopathic pulmonary fibrosis. Commonly referred to as IPF,
idiopathic pulmonary fibrosisis scarring or thickening of the lungs without a known cause. This fibrotic disease affects the lungs of patients and their ability to breathe.
No one knows what causes pulmonary fibrosis or why some people get it but the condition is believed to result from an inflammatory response to an unknown substance. "Idiopathic" means no cause can be found.
A study of twin veterans has linked antidepressant use to thicker arteries and therefore possibly increased risk of heart disease and stroke, according to data presented last week at the American College of Cardiology meeting in New Orleans.
The study included 513 middle-aged male twins who both served in the U.S. military during the Vietnam War. Twins are genetically the same but may be different when it comes to other risk factors such as diet, smoking and exercise, so studying them is a good way to distill out the effects of genetics.