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    Induced pluripotent stem cell research faces many challenges- but persistence pays off
    By Jennifer Wong | June 7th 2012 06:40 PM | Print | E-mail | Track Comments
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    My column covers the latest primary research discoveries in the life-science discipline. Much of what is reported here are considered discoveries...

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    Induced pluripotent stem cell (iPSC) research in the last 2 years has faced many twists and turns. With scientists uncovering a number of disturbing genomic abnormalities in these cells, the future of iPSC technology looked like a sea of despair.

    But lucky for those who persisted in this field of research, recent findings based on deep genome sequencing data revealed that these so-called "genomic abnormalities" simply reflect the normal genomic quirks of the original somatic cells from which iPSCs were derived. 

    References:
    Cheng et al, 2012 (Cell Stem Cell 10, 337–344)Young et al 2012 (Cell Stem Cell 10, 1-13)