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Neurim Pharmaceuticals has announced positive results from a phase II clinical study evaluating the efficacy and safety of Piromelatine (Neu-P11), a novel investigational multimodal sleep medicine developed for the treatment of patients with primary and co-morbid insomnia.

The new results are from a recent double-blind, randomized, placebo controlled, parallel group, non-confirmatory, sleep-laboratory study. The study evaluated piromelatine compared to placebo in 120 adult primary insomnia patients, ages 18 years and older. 

Surgeon Paolo Macchiarini,  Professor of Regenerative Surgery at Karolinska Institutet, has become famous worldwide due to successfully transplanting bioengineered stem cell-based trachea, composed of both artificial and biological material, in patients. That was an important waypoint on the road to the Big 5 organs, which are far largers and more complex.

Next up is the the esophagus and diaphragm and an experimental attempt to regenerate brain material in mice and rats, he said during his seminar at the scientific AAAS Annual Meeting in Boston. 

Science has always had a social component. Much of science is a neutral endeavor for the public good but in modern times the political component has meant navigating treacherous social and environmental policy waters. 

Not an easy task when science requires help from outside its field. Different social and science fields use different methods and scientists and policy makers rarely work together.  The government has taken over increased government control of projects and funding since World War II but modern problems mean that modern types of research centers are needed, as are new ways of organizing collaborations between scientists and policy makers - it can't be just political appointees handing out money to research the administration happens to like. 

Bacteria didn't just impact our evolution, we impacted the evolution of bacteria also, according to a study of DNA preserved in calcified bacteria on the teeth of ancient human skeletons.

The ancient genetic record reveals the negative changes in oral bacteria brought about by the dietary shifts as humans became farmers, and later with the introduction of food manufacturing in the Industrial Revolution.

Despite being in use for almost 20 years with no health or safety issues, controversy continues to surround genetically modified crops and their regulation.

Bruce Chassy, a professor emeritus of food science and human nutrition at the University of Illinois at Urbana-Champaign, believes that after thousands of research studies and worldwide planting, "genetically modified foods pose no special risks to consumers or the environment" and are over-regulated.

Engineers from the University at Buffalo engineers have created technology that could lead to breakthroughs in solar energy, stealth technology and other areas - but they had to catch some rainbows first. 

Qiaoqiang Gan, PhD, an assistant professor of electrical engineering at  the University at Buffalo, and a team of graduate students developed a "hyperbolic metamaterial waveguide," which is essentially an advanced microchip made of alternate ultra-thin films of metal and semiconductors and/or insulators. The waveguide halts and ultimately absorbs each frequency of light, at slightly different places in a vertical direction  to catch a "rainbow" of wavelengths.