This week in Science, Yale researchers present “roadmaps” showing that shared protons, a common loose link between two biological molecules, simply vibrate between the molecules as a local oscillator, rather than intimately entangling with the molecular vibrations of the attached molecules.

Led by Professor Mark A. Johnson in the Department of Chemistry, the new data reveal distinct, isolated vibrational patterns, solely associated with the bridging proton, that change dramatically according to the chemical properties of the tethered molecules.

Two oxygen atoms on different molecules are connected by their mutual attraction to an extra proton, shown as a fuzzy ball between them.

A drug under study to treat various cancers selectively kills cancer cells because of its affinity for a modified version of a critical heat shock protein they contain, researchers have found.

They found in cancer a modified version of heat shock protein 90, or hsp90, which like most heat shock proteins, promotes cell survival.

Research by Renee Theiss, Jason Kuo and C J Heckman, which has just been published in The Journal of Physiology, throws light on how information is processed in the Central Nervous System (CNS) to drive movement. The findings are relevant to understanding mechanisms underlying movement and disorders such as spinal cord injury and motor neurone disease (ALS).

The controversial idea that one cause of high blood pressure lies within the brain, and not the heart or blood vessels, has been put forward by scientists at the University of Bristol, UK, and is published this week in the journal Hypertension.

Dr. Hidefumi Waki, working in a research group led by Professor Julian Paton, has found a novel role for the protein, JAM-1 (junctional adhesion molecule-1), which is located in the walls of blood vessels in the brain.

Researchers have successfully applied X-ray scattering techniques to determine how dissolved metal ions interact in solution.

These findings will help researchers better understand how metal ions, such as those found in nuclear waste and other industrial processes, behave in the environment.

Researchers at the Department of Energy's Argonne National Laboratory and the University of Notre Dame have successfully applied X-ray scattering techniques to determine how dissolved metal ions interact in solution. Credit: Argonne National Laboratory

A new theoretical thermometer built from heavy-duty mathematics and computer code suggests that the surfaces of certain neutron stars run significantly hotter than previously expected. Hot enough, in fact, to at least partially answer an open question in astrophysics -- how to explain the observed frequency of ultra-violent explosions known as superbursts that sometimes ignite on such stars' surfaces?

Neutron star accreting matter from a red giant star. The red giant (on the upper right) is expanding and dumping material onto the neutron star. This material forms a disk and then finally falls to the neutron star surface. Credit: Tony Piro, U.C. Berkeley