A new study published in Cell Metabolism says it has increased the lifespan of middle-aged mice by 12% using a combination of three amino acids as supplements.
Branched-chain amino acids (BCAAs) have extended life span in yeast but this is the first time these amino acids have been shown to work in mammals, the researchers say.
In their study, some mice were fed a BCAA-enriched mixture (BCAAem) that contained the three amino acids (Leucine, isoleucine and valine) and it increased their average life span, improved muscle, and provided enhanced physical endurance. They also reported increased activity of SIRT1 in the mice, called the 'longevity' protein by some, and increased numbers of mitochondria, the 'power plants' of the cell.
Will it work in humans? Hard to know yet but an anti-aging role for BCAAs in any mammal is a good start.
Citation: Giuseppe D'Antona, Maurizio Ragni, Annalisa Cardile, Laura Tedesco, Marta Dossena, Flavia Bruttini, Francesca Caliaro, Giovanni Corsetti, Roberto Bottinelli, Michele O. Carruba, Alessandra Valerio, Enzo Nisoli, 'Branched-Chain Amino Acid Supplementation Promotes Survival and Supports Cardiac and Skeletal Muscle Mitochondrial Biogenesis in Middle-Aged Mice', Cell Metabolism, Volume 12, Issue 4, 362-372, 6 October 2010 DOI: 10.1016/j.cmet.2010.08.016
- PHYSICAL SCIENCES
- EARTH SCIENCES
- LIFE SCIENCES
- SOCIAL SCIENCES
Subscribe to the newsletter
Stay in touch with the scientific world!
Know Science And Want To Write?
- True Weight Loss Is Rare
- What May Be Missing From Quantum Computing - A Quantum Middle Man
- New GHOST Technology Leaps Out Of The Screen
- AMVA4NewPhysics Logo
- Genetic Testing In Kids - The Science Isn't Complicated But The Psychology Is
- Radiation Detectors Click By Design
- Patients With Recurrent Depression Have Smaller Hippocampi
- "Dr I think being obese is a mixture of the culture we grow up and lifestlye we choose to leave..."
- "Thank you for your words of encouragement. And, I agree that when it comes to weight control, the..."
- "Hi Bill, thanks for your message - I am considering your input. Maybe some more concept and less..."
- "Thanks for the tips - well indeed the internet is a complex place. But I did want some pink and..."
- "Apologizing for a hiatus due to vacations, I am posting today.... Yes Tommaso, how dare you allow..."
- What bee-killing mites can teach us about parasite evolution
- Autism - measured in a sniff
- Opera is deadly - but The Tarantino influence in modern opera is killing it
- Gene therapy for cystic fibrosis shows encouraging trial results
- Prion trials and tribulations: Finding the right tools and experimental models