A new study published in Cell Metabolism says it has increased the lifespan of middle-aged mice by 12% using a combination of three amino acids as supplements.
Branched-chain amino acids (BCAAs) have extended life span in yeast but this is the first time these amino acids have been shown to work in mammals, the researchers say.
In their study, some mice were fed a BCAA-enriched mixture (BCAAem) that contained the three amino acids (Leucine, isoleucine and valine) and it increased their average life span, improved muscle, and provided enhanced physical endurance. They also reported increased activity of SIRT1 in the mice, called the 'longevity' protein by some, and increased numbers of mitochondria, the 'power plants' of the cell.
Will it work in humans? Hard to know yet but an anti-aging role for BCAAs in any mammal is a good start.
Citation: Giuseppe D'Antona, Maurizio Ragni, Annalisa Cardile, Laura Tedesco, Marta Dossena, Flavia Bruttini, Francesca Caliaro, Giovanni Corsetti, Roberto Bottinelli, Michele O. Carruba, Alessandra Valerio, Enzo Nisoli, 'Branched-Chain Amino Acid Supplementation Promotes Survival and Supports Cardiac and Skeletal Muscle Mitochondrial Biogenesis in Middle-Aged Mice', Cell Metabolism, Volume 12, Issue 4, 362-372, 6 October 2010 DOI: 10.1016/j.cmet.2010.08.016
- PHYSICAL SCIENCES
- EARTH SCIENCES
- LIFE SCIENCES
- SOCIAL SCIENCES
Subscribe to the newsletter
Stay in touch with the scientific world!
Know Science And Want To Write?
- Are Marijuana Warning Labels Needed? Users Say Yes
- Order Patterned With Chaos - How Climate Is Predicted For Decades - With Exact Forecasts Only For Days
- Is The X(5568) A True Resonance ?
- Something is wrong in the Arctic
- John Glenn, Astronaut, and Senator dead at 95. A Milennial Perspective
- The Five Stages Of A Dying Theory
- Adolescent Obesity Linked To Permanent Bone Loss
- "Patrick, good to have you back writing about the Arctic condition. Neven has done a wonderful job..."
- "Just to say that I agree with Patrick. Science is not settled by voting and public opinion. Newton..."
- "We should name 2013 FY27 after the Potawatomi God of creation, Kche Mnedo. The Potawatomi are native..."
- "Another reminder. Please can you discuss the ideas rather than call people liars? Neither..."
- "A vigorous supporter of the Petition Project since its inception in 1998, Professor Seitz died..."
- A Possible Antidote for Carbon Monoxide Poisoning
- Surgeon General Declares War on E-Cigarettes But Not Marijuana, Hookah
- NHL's Concussion Protocol, a Closer Look (Part 2)
- Uh-Oh — Smokers Are Drinking the 'Additives Cause the Cancer' Kool-Aid
- A New Way to Prevent HIV Infection
- A Novel Way to Stop HIV