A new study published in Cell Metabolism says it has increased the lifespan of middle-aged mice by 12% using a combination of three amino acids as supplements.
Branched-chain amino acids (BCAAs) have extended life span in yeast but this is the first time these amino acids have been shown to work in mammals, the researchers say.
In their study, some mice were fed a BCAA-enriched mixture (BCAAem) that contained the three amino acids (Leucine, isoleucine and valine) and it increased their average life span, improved muscle, and provided enhanced physical endurance. They also reported increased activity of SIRT1 in the mice, called the 'longevity' protein by some, and increased numbers of mitochondria, the 'power plants' of the cell.
Will it work in humans? Hard to know yet but an anti-aging role for BCAAs in any mammal is a good start.
Citation: Giuseppe D'Antona, Maurizio Ragni, Annalisa Cardile, Laura Tedesco, Marta Dossena, Flavia Bruttini, Francesca Caliaro, Giovanni Corsetti, Roberto Bottinelli, Michele O. Carruba, Alessandra Valerio, Enzo Nisoli, 'Branched-Chain Amino Acid Supplementation Promotes Survival and Supports Cardiac and Skeletal Muscle Mitochondrial Biogenesis in Middle-Aged Mice', Cell Metabolism, Volume 12, Issue 4, 362-372, 6 October 2010 DOI: 10.1016/j.cmet.2010.08.016
- PHYSICAL SCIENCES
- EARTH SCIENCES
- LIFE SCIENCES
- SOCIAL SCIENCES
Subscribe to the newsletter
Stay in touch with the scientific world!
Know Science And Want To Write?
- What Americans Fear Most Isn't Ebola Or Terrorism, It's...
- Great Earthquakes Doubled In The Most Recent 10 Year Period - What That Means
- ECFA Workshop: Planning For The High Luminosity LHC
- Why Climate 'Uncertainty' Is No Excuse For Doing Nothing
- Moderate Pot Use By Adolescents Doesn't Hurt IQ
- Dams Are Not The Smart Way To Secure Water For Agriculture
- Cosmic Rays Jeopardize Deep-Space Astronaut Missions
- "Limiting global warming to 2 degrees C this century is not the problem that most scientists once..."
- "An interesting read, but perhaps not ideal for me to make one of my hot-headed comments right off..."
- "“I accept that if my child kicks lions, this will irritate them, but a range of factors will..."
- "Yes in fact it is free, I just looked it up in the Apple Store. Actually you have it backwards..."
- "You believe in every possibility? So you believe in gods and in an absence of gods, all at the..."
- Beyond universal donors, some poeple are programed with no blood type at all
- Anti-conventional ag movement spurs Big Ag to look to organic pesticides
- Can people really inherit memories?
- An end to fat shaming? The 50 year DNA mystery of metabolic dysfunction may soon be solved
- Egg freezing: a smart career move?
- Women carry fetal DNA long after children’s birth
- Global consumption an increasingly significant driver of tropical deforestation
- An effective, cost-saving way to detect natural gas pipeline leaks
- Susceptibility for relapsing major depressive disorder can be calculated
- Indiana Project screenings show need for more mental health services in youth detention
- Aphthous ulcers: Causes of mucosal inflammation are unclear