Obesity, along with diabetes and associated consequences like cardiovascular, neurological and renal diseases, is increasing worldwide. Along with focusing on smarting eating, research is on to understand the biological mechanisms.
In obesity, fatty acids, derived mostly from adipose tissue, alter lipid metabolism in other tissues such as liver and skeletal muscles. Both impaired fatty acid metabolism and glucose are hallmarks of diabetes.
In a recent study in the journal Biochemistry, a research group applied fluorescent methods to measure the rate by which fatty acids bind to and move across the fatty acid membrane to become metabolized.