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    Thanks But No Thanks For AIDS Comparison, Say Chagas Disease Experts
    By Hank Campbell | June 3rd 2012 03:30 AM | 23 comments | Print | E-mail | Track Comments
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    "Chagas Disease: “The New HIV/AIDS of the Americas”" screams the headline of an editorial in the open access journal PLoS Neglected Tropical Diseases, written primarily by two principal investigators of a vaccine against Chagas disease - and it has resounded with a thud among the actual people they think they are helping.

    “I think it’s an unfortunate comparison,” Rick Tarleton, a distinguished research professor at the University of Georgia studying Chagas disease and president of the Chagas Disease Foundation, told ABC News. “There are stigmas attached to HIV/AIDS that themselves are inappropriate, but it would be even more inappropriate to apply them to something like Chagas disease.”

    Unless you are trying to get attention for your research, it seems obvious they have little in common.  Chagas disease is an infection transmitted to humans by blood-sucking insects, it has nothing to do with drug use or unprotected sex. In other words, Chagas disease is egalitarian and exculpatory and, as politically incorrect as it is to state the obvious, most cases of AIDS are not. No one is intentionally attaching a blood-sucking insect to themselves but lots of dumb people have unprotected sex and use dirty needles despite decades of awareness, condom giveaways and needle exchanges.

    Trypanosoma cruzi in triatomine bugs chagas disease
    Trypanosoma cruzi in triatomine bugs. Photo: CDC

    The authors of the editorial nonetheless contend there are "striking similarities" - more poor people get AIDS, they say, and the same with Chagas disease.   Drugs are expensive for AIDS, they say, same with Chagas disease. The mainstream media dutifully complied, crafting their scare journalism for the week.

    And yet they did not compare Chagas disease to lung cancer, which also shares those demographic characteristics. Dr. Peter Hotez, dean of Baylor College of Medicine’s National School of Tropical Medicine, told ABC the editorial was written so provocatively to rally resources for people with Chagas disease.  Is that wise, or will it cause people to become jaded when someone with an authoritative position massages data for bombastic effect? 

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    “I don’t think the comparison to HIV/AIDS is a realistic one, and I don’t expect it to serve the situation terribly well,” said Tarleton.

    Indeed, if it is even discovered, and many people live their lives without ever knowing they have it, Chagas disease can be treated in three months - though it is costly.  Still, that is not possible with AIDS.  And it is largely preventable, though poor people in South America often lack the means to even do that - insecticide can prevent the bugs from being around to bite anyone. There's no insecticide for HIV.

    “I was surprised, frankly, at the whole tone of the editorial,” Dr. William Schaffner, chair of preventive medicine at Vanderbilt University Medical Center in Nashville, Tenn., and president of the National Foundation for Infectious Diseases told Katie Moisse. “But I hope it shifts the view from forgotten problems of forgotten people to newly recognized and appreciated problems of people who need help.”

    Those are actually pretty stern words, if you know anything about researchers and how they prefer to sound when going on the record about other researchers. Alarmist rhetoric has become an increasing problem because it has been shown to be effective time and again, and it sure got attention for an obscure editorial in a small journal. But it isn't good for society much less the tens of millions of people in poor countries who are the primary victims of this disease - who could now be unfairly perceived because a small group of researchers felt like they were helping.

    Links:

    Chagas the New AIDS? Experts Disagree by Katie Moisse, ABC News

    Peter J. Hotez, Eric Dumonteil, Laila Woc-Colburn, Jose A. Serpa, Sarah Bezek, Morven S. Edwards, Camden J. Hallmark, Laura W. Musselwhite, Benjamin J. Flink, Maria Elena Bottazzi, 'Chagas Disease: “The New HIV/AIDS of the Americas”',  PLoS Negl Trop Dis 6(5): e1498. doi:10.1371/journal.pntd.0001498

    Comments

    So concerned are you about stigma that you lovingly reproduce it in this article. Just as the Chagas researchers found the HIV comparison unhelpful, thousands of HIV prevention researchers and workers and people living with HIV are applying their heads to their desks, repeatedly and with force, upon reading this article. Science 2.0 sounds an awful lot like Stigma 101, it seems.

    Hank
    How am I stigmatizing anything by pointing out that exaggerated comparisons that the actual afflicted people don't want (and are deceptive, and thus lessen the trust of the public) are doing more harm than good?  What stigma is this at all?  There are 300,000 people in the US with chagas disease, they are not stigmatized - most people have never heard of it.  The people stigmatizing it are the ones who seek to drag it into a cultural war.
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    I've never seen an article where nearly every paragraph is a single sentence! You obviously have a lot to say, and feel strongly about the subject, but breathing occasionally is still required. Try reading this story aloud.

    Hank
    You almost had me on this one - I do tend to run on - so I checked.  The first paragraph is one sentence but all the rest, no.  I need to work on being interesting enough for people to read more than one paragraph, I suppose.  
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    I'd like to say a few things to you...
    1. AIDs and HIV are NOT interchangeable, they are two completely different things. HIV is a virus, one that you get from blood, semen, vaginal fluids, and breast milk, this is what you are talking about in your article. AIDs is a syndrome, one you get from getting opportunistic infections. Not everyone who has AIDs has HIV, they may have cancer or another disease that weakens the immune system.
    2. This sentence: "In other words, Chagas disease is egalitarian and exculpatory and, as politically incorrect as it is to state the obvious, most cases of AIDS are not." When you say AIDs there, it should say HIV.... and HIV is a virus, it will enter any body when it gets the opportunity, it does not care who you are.
    Then you continue to say: " No one is intentionally attaching a blood-sucking insect to themselves but lots of dumb people have unprotected sex and use dirty needles despite decades of awareness, condom giveaways and needle exchanges." Not everyone who has HIV (or as you would say AIDs) is dumb. Sometimes condoms break or the person that they're having sex with is their longtime boyfriend/girlfriend and they trust him/her, but the person doesn't know (s)he even has HIV! You cannot say that everyone with HIV is dumb!
    Next article you post I would suggest actually doing some research before saying anything on the subject.

    Hank
    So you are saying HIV does not cause AIDS?
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    If you have HIV it will eventually progress to AIDs, however if you have AIDs it does not necessarily mean you have HIV. HIV is a virus that weakens the immune system, causing you to have opportunistic infections, those infections are what lead to AIDs. If you have AIDs though, you can fix your HIV medication and go back to having HIV, no longer having AIDs.

    Hank
    And you say I need to do research?   You have just overturned all of epidemiology.
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    I work in an HIV research facility.

    Hank
    An astrologer may work at the LHC somewhere - that does not mean that if they claim the LHC will cause a black hole to consume the planet there is a science basis to it.  You are contending because you have anonymous credentials at an unspecific research facility you can reverse AIDS and HIV does not cause it.  That is in defiance of epidemiology.
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    AIDs is caused by the opportunistic infections, not HIV itself. You can get AIDs from any diseaae that destroys your immune system; a lot of people with cancer have AIDs.
    If you have HIV and have just progressed to AIDs you can reverse it by fixing your medication and progress back to HIV. You will eventually die of AIDs, but yes, it can be reversed if not progressed far.

    Gerhard Adam
    Sorry, but I'm going to need to see some citations here.  You're making absolutely no sense.

    http://www.cdc.gov/hiv/topics/basic/
    Hank
    Well, the CDC got much more broad with 'AIDS' in the early 1990s but everything else you have written is dead wrong.
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    Hank
    We all know there is a difference.  You are claiming that AIDS is not caused by HIV and that you can cure it/reverse it.   None of that has anything to do with chagas disease, but you seem to think that the same number of people get AIDS the way chagas victims do.  It is just a snowball of incorrect information.
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    AIDs is NOT caused by HIV, it is caused by the opportunistic infections. You obviously did not read anything that I had sent you... You cannot CURE AIDs, however if it is not progressed far enough, you can fix your HAART medication and go back to having HIV. Anyone who got HIV in the 80's has at some point progressed to AIDs, find someone with AIDs from the 80's and ask them if you don't believe me. Or do some research.
    And I am not talking about the Chagas disease, I do not know anything about it, therefore I will not comment on it. " None of that has anything to do with chagas disease, but you seem to think that the same number of people get AIDS the way chagas victims do." I never said anything relating to this.

    Gerhard Adam
    You need to read your own links:
    AIDS usually takes time to develop from the time a person acquires HIV – usually between 2 to 10–15 years.
    You're mistaken about AIDS being caused by opportunistic infections. 
    I know how long it can take. As I've said before, HIV weakens the immune system, then you get opportunistic infections, those infections you cannot fight off because the weakened immune system.

    Gerhard Adam
    Sorry, but you're simply wrong.  HIV weakens the immune system, but AIDS is the failure of that immune system which is then subject to opportunistic infections.  It makes no sense otherwise, since ALL infections are, by definition, opportunistic.  The reason it becomes a problem is because AIDS is what enables those infections to gain traction. 

    It appears that you are confusing the difference between opportunistic infections due to HIV, versus those in AIDS.   The role of HAART is to reduce the amount of HIV which can help restore the immune system and reduce opportunistic infections in HIV-positive patients.  It has NOTHING to do with AIDS.

    http://www.avert.org/hiv-opportunistic-infections.htm
    Hello there,

    To mitigate the confusion, here, once again, is an interview with Lus Montaignier, Nobelprize winner and discoverer of HIV virus:

    http://www.youtube.com/watch?v=WQoNW7lOnT4

    It seems Willow is simply insisting that any immune deficiency that is acquired is AIDS because that is the literal meaning of the words of the acronym. Kind of like insisting that Canada is a USA because it is a united nation-state in the Americas. Not all that interesting a fallacy to keep addressing.

    As for single sentence paragraphs, yours are fine. It takes a special kind of mind to get annoyed at arbitrary grammatical rules when the message itself is clear as day. Would the OP complain about chapter 42, "On the Whiteness of the Whale" of Moby Dick?

    "Though in many natural objects, whiteness refiningly enhances beauty, as if imparting some special virtue of its own, as in marbles, japonicas, and pearls; and though various nations have in some way recognised a certain royal preeminence in this hue; even the barbaric, grand old kings of Pegu placing the title "Lord of the White Elephants" above all their other magniloquent ascriptions of dominion; and the modern kings of Siam unfurling the same snow-white quadruped in the royal standard; and the Hanoverian flag bearing the one figure of a snow-white charger; and the great Austrian Empire, Caesarian, heir to overlording Rome, having for the imperial color the same imperial hue; and though this pre-eminence in it applies to the human race itself, giving the white man ideal mastership over every dusky tribe; and though, besides, all this, whiteness has been even made significant of gladness, for among the Romans a white stone marked a joyful day; and though in other mortal sympathies and symbolizings, this same hue is made the emblem of many touching, noble things- the innocence of brides, the benignity of age; though among the Red Men of America the giving of the white belt of wampum was the deepest pledge of honor; though in many climes, whiteness typifies the majesty of Justice in the ermine of the Judge, and contributes to the daily state of kings and queens drawn by milk-white steeds; though even in the higher mysteries of the most august religions it has been made the symbol of the divine spotlessness and power; by the Persian fire worshippers, the white forked flame being held the holiest on the altar; and in the Greek mythologies, Great Jove himself being made incarnate in a snow-white bull; and though to the noble Iroquois, the midwinter sacrifice of the sacred White Dog was by far the holiest festival of their theology, that spotless, faithful creature being held the purest envoy they could send to the Great Spirit with the annual tidings of their own fidelity; and though directly from the Latin word for white, all Christian priests derive the name of one part of their sacred vesture, the alb or tunic, worn beneath the cassock; and though among the holy pomps of the Romish faith, white is specially employed in the celebration of the Passion of our Lord; though in the Vision of St. John, white robes are given to the redeemed, and the four-and-twenty elders stand clothed in white before the great-white throne, and the Holy One that sitteth there white like wool; yet for all these accumulated associations, with whatever is sweet, and honorable, and sublime, there yet lurks an elusive something in the innermost idea of this hue, which strikes more of panic to the soul than that redness which affrights in blood."

    Hank
    I did change the sentence, mostly because I was not getting the analogy to work.  While I am proud of my ability to run on, I suppose I need a lot of work to be a great enough author to pull off the sentence above.
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    I read this article after I watched a documentary on Chagas on http://topdocumentarystream.com/the-last-kiss/. Appreciate for raising awareness